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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [24]
上海应用物理研究所 [4]
古脊椎动物与古人类研... [1]
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OAI收割 [29]
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期刊论文 [25]
会议论文 [4]
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2022 [1]
2020 [2]
2019 [1]
2018 [3]
2016 [2]
2015 [2]
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The history of agriculture in the mountainous areas of the lower Yangtze River since the late Neolithic
期刊论文
OAI收割
FRONTIERS OF EARTH SCIENCE, 2022, 页码: 10
作者:
Wang, Jingyi
;
Chen, Xiaochun
;
Zhang, Guilin
;
Zhang, Guowen
;
Wu, Yan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/22
southern Anhui
Jingshuidun site
rice
millet
phytolith
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
Natural product piperine alleviates experimental allergic encephalomyelitis in mice by targeting dihydroorotate dehydrogenase
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:
Liu, Zehui
;
Hu, Qian
;
Wang, Wanyan
;
Lu, Sisi
;
Wu, Dang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
Multiple sclerosis
DHODH
Piperine
Natural product
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:
Zhang, Xianglei
;
Dong, Guangyu
;
Li, Heng
;
Chen, Wuyan
;
Li, Jian
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells
期刊论文
OAI收割
HAEMATOLOGICA, 2018, 卷号: 103, 期号: 9, 页码: 1472-1483
作者:
Wu, Dang
;
Wang, Wanyan
;
Chen, Wuyan
;
Lian, Fulin
;
Lang, Li
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
irondysregulatesappprocessingaccompanyingwithsappacellularretentionandsecretaseinhibitioninratcorticalneurons
期刊论文
OAI收割
actapharmacologicasinica, 2018, 卷号: 39, 期号: 2, 页码: 177
作者:
Chen Yuting
;
Chen Wuyan
;
Huang Xiaotian
;
Xu Yechun
;
Zhang Haiyan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
iron
neurons
amyloid precursor protein
sAPPα
β-amyloid
β-secretase
Alzheimer's disease
Iron dysregulates APP processing accompanying with sAPPa cellular retention and β-secretase inhibition in rat cortical neurons
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2018, 卷号: 39, 期号: 2, 页码: 177
作者:
Chen Yuting
;
Chen Wuyan
;
Huang Xiaotian
;
Xu Yechun
;
Zhang Haiyan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
iron
neurons
amyloid precursor protein
sAPPα
β-amyloid
β-secretase
Alzheimer's disease
Structural and Thermodynamic Characterization of Protein-Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 10, 页码: 5115-5120
作者:
Liu, Qiufeng
;
Chen, Xinde
;
Chen, Wuyan
;
Yuan, Xiaojing
;
Su, Haixia
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Structure-Based Discovery of PDEs Inhibitors
期刊论文
OAI收割
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2016, 卷号: 16, 期号: 9, 页码: 917-933
作者:
Li, Li
;
Chen, Wuyan
;
Chen, Tiantian
;
Ren, Jing
;
Xu, Yechun
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Crystal structure
Cyclic nucleotide signalling pathway
Family-selective inhibitor
Medicinal chemistry
Phosphodiesterases
Structure-based drug design
Design, synthesis and biological evaluation of tasiamide B derivatives as BACE1 inhibitors
期刊论文
OAI收割
Bioorganic & medicinal chemistry, 2015, 卷号: 23, 期号: 9, 页码: 1963-74
作者:
Liu, Jian
;
Chen, Wuyan
;
Xu, Yechun
;
Ren, Sumei
;
Zhang, Wei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08