机构

• 上海药物研究所 [38]
• 上海应用物理研究所 [8]
• 金属研究所 [3]
• 广州地球化学研究所 [2]
• 宁波材料技术与工程研... [2]
• 成都生物研究所 [2]
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采集方式

• OAI收割 [60]
• iSwitch采集 [2]

内容类型

• 期刊论文 [61]
• 会议论文 [1]

发表日期

• 2025 [3]
• 2024 [4]
• 2023 [3]
• 2022 [4]
• 2021 [3]
• 2020 [2]
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学科主题

• Energy & F... [1]
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浏览/检索结果: 共62条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of novel Ebola entry inhibitors with 1,2,3,4-tetrahydroisoquinoline-3-carboxamide based on (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 123, 页码: 4 作者:  Lin, Junzhen;  Xiao, Fuling;  Han, Sheng;  Hu, Youhong;  Zuo, Jianping   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/06/23 Ebola virus entry inhibitor  Tetrahydroisoquinoline   Novel Aryl Sulfonium Modification on Vancomycin to Tackle MRSA and VRE In Vitro and In Vivo through Dual Enhanced Cell-Wall and Membrane Inhibition 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8310-8329 作者:  Xie, Yuanyuan;  Wang, Xiaowen;  Chang, Taopeng;  Chen, Zhifu;  Luo, Youhong   |  收藏  |  浏览/下载：11/0  |  提交时间：2025/06/23 Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10 作者:  Zeng, Yanping;  Xiao, Jian;  Shi, Li;  Li, Yangsha;  Xu, Yuanxin   |  收藏  |  浏览/下载：63/0  |  提交时间：2025/04/01 LC3B  CDK9  Degradation  Protein complex   Single Amine or Guanidine Modification on Norvancomycin and Vancomycin to Overcome Multidrug-Resistance through Augmented Lipid II Binding and Increased Membrane Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20639-20663 作者:  Bian, Xiaolei;  Chen, Zhifu;  Li, Fang;  Xie, Yuanyuan;  Li, Yi   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/12/11 Structural Optimization of Isoquinoline Derivatives from Lycobetaine and Their Inhibitory Activity against Neuroendocrine Prostate Cancer Cells 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 18, 页码: 28 作者:  Zhang, Zhuo;  Shen, Qianqian;  Ji, Yiyi;  Ma, Yanjie;  Hou, Haiyang   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/11/05 NEPC  natural product  natural product derivatives  lycobetaine   A novel BODIPY-based theranostic agent for in vivo fluorescence imaging of cerebral Aβ and ameliorating Aβ-associated disorders in Alzheimer's disease transgenic mice 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2024, 页码: 9 作者:  Zhang, Jingjing;  Ren, Wenming;  Liu, Xiaohui;  Chen, Jingjing;  Zeng, Yuteng   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/05/07 A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2024, 卷号: 221, 页码: 14 作者:  Yang, Li;  Gong, Ying;  Liu, Feifei;  Chen, Wuhong;  Wang, Xinran   |  收藏  |  浏览/下载：38/0  |  提交时间：2024/02/19 Hepatitis B virus  Capsid assembly  Phthalazinone derivatives  Apoptosis   Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17 作者:  Zeng, Yanping;  Xiao, Jian;  Xu, Yuanxin;  Wei, Fan;  Tian, Lina   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8 作者:  Chen, Wuhong;  Gong, Ying;  Long, Guozhang;  Wang, Xinran;  Yang, Yurong   |  收藏  |  浏览/下载：31/0  |  提交时间：2023/10/17 HBV  Capsid assembly modulators  Prodrug  Hepatitis B surface antigen   Experimental Study on the Depressurization of Methane Hydrate in the Clayey Silt Sediments via Hydraulic Fracturing 期刊论文  OAI收割 ENERGY & FUELS, 2023, 卷号: 37, 期号: 6, 页码: 4377 作者:  Wang, Xiaochu;  Sun, Youhong;  Chen, Hangkai;  Peng, Saiyu;  Jiang, Shuhui   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/08/02