中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
地理科学与资源研究... [10]
上海药物研究所 [10]
西双版纳热带植物园 [5]
海洋研究所 [5]
高能物理研究所 [3]
力学研究所 [2]
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OAI收割 [48]
内容类型
期刊论文 [38]
CNKI期刊论文 [5]
会议论文 [2]
专利 [1]
专著章节/文集论文 [1]
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2024 [4]
2023 [3]
2022 [7]
2020 [4]
2019 [2]
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Physics [1]
X196 [1]
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One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18
作者:
Li, Huaxuan
;
Yang, Hong
;
Liu, Li
;
Zheng, Jiahong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/12/11
Protein arginine methyltransferase 5
Nucleoside derivatives
Piperazine
Metabolic stability
Symmetric dimethylarginines
Discovery of CZL-046 with an (
S
)-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 20, 页码: 18606-18628
作者:
Chen, Zonglong
;
Yang, Hong
;
Zhang, Yan
;
Lyu, Xiaodong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/05
Multi-elemental stoichiometric ratios of atmospheric wet deposition in Chinese terrestrial ecosystems
期刊论文
OAI收割
ENVIRONMENTAL RESEARCH, 2024, 卷号: 245, 页码: 8
作者:
Chen, Yanran
;
Wang, Qiufeng
;
Zhu, Jianxing
;
Yang, Meng
;
Hao, Tianxiang
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2024/04/01
N: P ratio
Stoichiometry
Wet deposition
Multi-element
Spatial pattern
Temporal dynamic
Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19
作者:
Chen, Yuting
;
Wang, Zekun
;
Zhang, Junjie
;
Shi, Qiongyu
;
Yang, Hong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/05/07
PRMT5
Nucleoside derivatives
Methyltransferases
Structure -activity relationship
Discovery of a PROTAC degrader for METTL3-METTL14 complex
期刊论文
OAI收割
CELL CHEMICAL BIOLOGY, 2024, 卷号: 31, 期号: 1, 页码: 25
作者:
Du, Wenhao
;
Huang, Yuting
;
Chen, Xiaoai
;
Deng, Yue
;
Sun, Yaoliang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/07
Atmospheric wet organic nitrogen deposition in China: Insights from the national observation network
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 898, 页码: 165629
作者:
Xi, Yue
;
Wang, Qiufeng
;
Zhu, Jianxing
;
Yang, Meng
;
Hao, Tianxiang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/09/07
Nitrogen deposition
Organic nitrogen
China
Spatial pattern
Influencing factors
Ecological effects
Structural Modification and Pharmacological Evaluation of Substituted Quinoline-5,8-diones as Potent NSD2 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18
作者:
Tang, Hairong
;
Yu, Aisong
;
Xing, Li
;
Chen, Xiaoyu
;
Ding, Huaqian
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/04/10
Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20
作者:
Chen, Yuting
;
Shi, Qiongyu
;
Yang, Hong
;
Li, Jiayi
;
Zhou, Kaixin
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2023/04/10
Epigenetic
PRMT5 inhibitor
Nucleoside derivatives
Structure-activity Relationship Prodrug
Atmospheric silicon wet deposition and its influencing factors in China
期刊论文
OAI收割
ENVIRONMENTAL RESEARCH, 2022, 卷号: 214, 页码: 8
作者:
Xi, Yue
;
Wang, Qiufeng
;
Zhu, Jianxing
;
Zhang, Qiongyu
;
Chen, Yanran
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/11/09
Silicon deposition
Spatial pattern
Annual variation
Influencing factor
Chinese terrestrial ecosystem
Atmospheric silicon wet deposition and its influencing factors in China
期刊论文
OAI收割
ENVIRONMENTAL RESEARCH, 2022, 卷号: 214, 页码: 8
作者:
Xi, Yue
;
Wang, Qiufeng
;
Zhu, Jianxing
;
Zhang, Qiongyu
;
Chen, Yanran
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/11/09
Silicon deposition
Spatial pattern
Annual variation
Influencing factor
Chinese terrestrial ecosystem