中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
大连化学物理研究所 [15]
上海药物研究所 [6]
金属研究所 [2]
云南天文台 [2]
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OAI收割 [32]
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期刊论文 [31]
专利 [1]
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2025 [1]
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Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679
作者:
Jin, Yuheng
;
Qi, Xuxin
;
Yu, Xiaoli
;
Cheng, Xirui
;
Chen, Boya
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/06/23
HDAC7
PROTAC
Selectivity
Hematologic malignancies
Non-enzymatic function
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:
Zhang, Jingyu
;
Duan, Haiting
;
Gui, Renzhao
;
Wu, Mingfei
;
Shen, Liteng
  |  
收藏
  |  
浏览/下载:158/0
  |  
提交时间:2023/12/19
Acute myeloid leukemia
Bromodomain-containing protein 9
Proteolysis-targeting chimera
Orally bioavailable
Docking
Single-cell RNA sequencing reveals the suppressive effect of PPP1R15A inhibitor Sephin1 in antitumor immunity
期刊论文
OAI收割
ISCIENCE, 2023, 卷号: 26, 期号: 2, 页码: 27
作者:
Wang, Rongjing
;
Zhang, Yuchao
;
Guo, Shiwei
;
Pei, Siyu
;
Guo, Wei
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/10/17
Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton's Tyrosine Kinase for the Treatment of Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9096–9125
作者:
Zhang, Jingyu
;
Che, Jinxin
;
Luo, Xiaomin
;
Wu, Mingfei
;
Kan, Weijuan
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2024/03/21
Anisotropic cyclic plasticity modeling for additively manufactured nickel-based superalloys
期刊论文
OAI收割
FATIGUE & FRACTURE OF ENGINEERING MATERIALS & STRUCTURES, 2022, 页码: 17
作者:
Jin, Shengzhe
;
Sun, Jingyu
;
Yuan, Huang
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/07/18
anisotropy
cyclic plasticity
fatigue
multiaxial loading
selective laser melting (SLM)
Microbiologically influenced corrosion of TiZrNb medium-entropy alloys by Desulfovibrio desulfuricans
期刊论文
OAI收割
JOURNAL OF ALLOYS AND COMPOUNDS, 2021, 卷号: 875, 页码: 15
作者:
Wei, Boxin
;
Pang, Jingyu
;
Xu, Jin
;
Sun, Cheng
;
Zhang, Hongwei
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/10/15
Microbiologically influenced corrosion
Medium-entropy alloy
Desulfovibrio desulfuricans
EIS
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
期刊论文
OAI收割
AUTOPHAGY, 2021, 卷号: 17
作者:
Klionsky, Daniel J.
;
Abdel-Aziz, Amal Kamal
;
Abdelfatah, Sara
;
Abdellatif, Mahmoud
;
Abdoli, Asghar
  |  
收藏
  |  
浏览/下载:348/0
  |  
提交时间:2021/05/31
Autophagosome
cancer
flux
LC3
lysosome
macroautophagy
neurodegeneration
phagophore
stress
vacuole
A New Sensor for Simultaneous Measurement of Strain and Temperature
期刊论文
OAI收割
IEEE Photonics Technology Letters, 2020, 卷号: 32, 期号: 19, 页码: 1253-1256
作者:
Sun, Cuiting
;
Lu, Chupeng
;
Jin, Xiren
;
Chen, Xudong
;
Yan, Qi
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/10/09
Cascaded structure
long-period fiber grating
simultaneous measurement
strain
temperature
Characterization of anti-BCG benz[alpha]anthraquinones and new siderophores from a Xinjiang desert-isolated rare actinomyceteNocardiasp. XJ31
期刊论文
OAI收割
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2020, 卷号: 104, 期号: 19, 页码: 8267-8278
作者:
Zhang, Li
;
Zhang, Jingyu
;
Ren, Biao
;
Lu, Wanying
;
Hou, Chengjian
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/12/24
Xinjiang desert
Nocardiasp
Anti-BCG
Brasiliquinone
Nocardimicin
Structural basis of GPBAR activation and bile acid recognition
期刊论文
OAI收割
NATURE, 2020, 页码: 29
作者:
Yang, Fan
;
Mao, Chunyou
;
Guo, Lulu
;
Lin, Jingyu
;
Ming, Qianqian
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/24