机构

• 上海药物研究所 [25]
• 西北高原生物研究所 [9]
• 海洋研究所 [3]
• 沈阳自动化研究所 [3]
• 力学研究所 [2]
• 金属研究所 [2]
• 更多

采集方式

• OAI收割 [62]
• iSwitch采集 [1]

内容类型

• 期刊论文 [58]
• 专利 [3]
• 会议论文 [2]

发表日期

• 2025 [4]
• 2024 [4]
• 2023 [3]
• 2022 [9]
• 2021 [5]
• 2020 [2]
• 更多

学科主题

• Geology [1]
• Geoscience... [1]
• 期刊论文 [1]

筛选

浏览/检索结果: 共63条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16 作者:  Zeng, Gongruixue;  Xu, Gaoya;  Gao, Lixin;  Zheng, Xiaoli;  Chi, Xinglong   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/04/01 Proteasome inhibitors  Macrocycle  Stability  Anti-cancer activities   Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679 作者:  Jin, Yuheng;  Qi, Xuxin;  Yu, Xiaoli;  Cheng, Xirui;  Chen, Boya   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/06/23 HDAC7  PROTAC  Selectivity  Hematologic malignancies  Non-enzymatic function   Cavity oscillation drives pattern formation in early mammalian embryos 期刊论文  OAI收割 CELL REPORTS, 2025, 卷号: 44, 期号: 3, 页码: 115342 作者:  Guo, Zheng;  Yao, Jie;  Zheng X(郑旭);  Cao, Jialing;  Lv, Xinxin   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/07/21 cavity oscillation  EPI/PrE segregation  pattern formation  early mammalian embryos  blastocyst   Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15 作者:  Chen, Jiexuan;  Wu, Mingfei;  Mo, Jun;  Hong, Ju;  Wang, Wei   |  收藏  |  浏览/下载：20/0  |  提交时间：2025/04/01 Discovery of N-Benzylpiperidinol derivatives as USP7 inhibitors against Hematology 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 13 作者:  Pan, Youlu;  Chen, Haifeng;  Fu, Jingfeng;  Zhang, Jingyu;  Wang, Peipei   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/10/21 Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10 作者:  Yu, Qian;  Gao, Lixin;  Xu, Linhao;  Han, Yubing;  Cao, Yu   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/12/11 Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 28 作者:  Duan, Haiting;  Zhang, Jingyu;  Gui, Renzhao;  Lu, Yang;  Pang, Ao   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/08/20 Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 21 作者:  Lu, Yang;  Gao, Jian;  Wang, Peipei;  Chen, Haifeng;  He, Xinjun   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/07/12 Hepatocellular carcinoma  Ubiquitin-specific protease 10  Deubiquitination  Selectivity   Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18 作者:  Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng   |  收藏  |  浏览/下载：155/0  |  提交时间：2023/12/19 Acute myeloid leukemia  Bromodomain-containing protein 9  Proteolysis-targeting chimera  Orally bioavailable  Docking   The development and benefits of metformin in various diseases 期刊论文  OAI收割 FRONTIERS OF MEDICINE, 2023, 页码: 44 作者:  Dong, Ying;  Qi, Yingbei;  Jiang, Haowen;  Mi, Tian;  Zhang, Yunkai   |  收藏  |  浏览/下载：33/0  |  提交时间：2023/10/17 metformin  metabolism  cancer  aging  neurological disorder