机构

• 上海药物研究所 [7]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2023 [1]
• 2022 [1]
• 2021 [2]
• 2020 [1]
• 2019 [2]

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 10 作者:  Li, Peizhuo;  Tian, Yucheng;  Shang, Qinghong;  Tang, Cailing;  Hou, Zeng   |  收藏  |  浏览/下载：32/0  |  提交时间：2023/10/17 NPAS3  Covalent inhibitor  Protein -protein interaction  5-nitrothiazole warhead   Discovery of Potent Small-Molecule USP8 Inhibitors for the Treatment of Breast Cancer through Regulating ERα Expression 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 8914-8932 作者:  Tian, Yucheng;  Liu, Kang;  Liu, Ruoyi;  Qiu, Zhixia;  Xu, Yifan   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/21 Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52, 页码: 12 作者:  Ding, Hong;  Pei, Yuan;  Li, Yuanqing;  Xu, Wen;  Mei, Lianghe   |  收藏  |  浏览/下载：46/0  |  提交时间：2022/06/15 Epigenetics  Histone acetyltransferase  P300/CBP  Ovarian cancer   Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11 作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan   |  收藏  |  浏览/下载：30/0  |  提交时间：2021/05/24 CDK9  Antitumor  PROTAC  AML  Degrader   Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9 作者:  Han, Jie;  Tian, Yucheng;  Yu, Liang;  Zhang, Qilin;  Xu, Xi   |  收藏  |  浏览/下载：51/0  |  提交时间：2020/12/24 Ubiquitination  High throughput screening  Drug discovery  USP8   Development and Characterization of a Fluorescent Probe for GLS1 and the Application for High-Throughput Screening of Allosteric Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 21, 页码: 9642-9657 作者:  Xu, Xi;  Kuang, Zijian;  Han, Jie;  Meng, Ying;  Li, Lei   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/03/21 Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 782-801 作者:  Wang, Jubo;  Li, Tinghan;  Zhao, Tengteng;  Wu, Tizhi;  Liu, Chuang   |  收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01 Wogonin  CDK9  AML  Flavonoid  Antitumor