中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
化学研究所 [46]
昆明植物研究所 [41]
上海药物研究所 [37]
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期刊论文 [490]
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2025 [4]
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Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 653, 页码: 13
作者:
Sun, Ming-Dao
;
Lin, Qin
;
Ramezani, Jahandar
;
Liu, Jiang-Si
;
Lu, Zheng-An
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/04/03
Early Cretaceous
Aptian
CA-ID-TIMS geochronology
Astrochronology
Carbon isotope stratigraphy
Presence and sources of per- and polyfluoroalkyl substances (PFASs) in the three major rivers on Hainan Island
期刊论文
OAI收割
ENVIRONMENTAL RESEARCH, 2025, 卷号: 266, 页码: 15
作者:
Tang, Wang-Qing
;
Wang, Tuan-Tuan
;
Miao, Jiang-Wei
;
Tan, Hua-Dong
;
Zhang, Hong-Jin
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/03
PFASs
Hainan Island
Occurrence
Risk assessment
Rivers
Chemical profiling and comparative analysis of different parts of
Asarum
heterotropoides
using SPME-GC-QTOF-MS and LC- Orbitrap-MS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 252, 页码: 9
作者:
Hu, Yun-shu
;
Zhang, Jian-qing
;
Xu, Meng
;
Yang, Huan-ya
;
Liu, Chun-xiang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/11/26
Asari radix et rhizoma
A. heterotropoides
SPME-GC-MS
LC-Orbitrap-MS
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/04/01
Targeting 5-Hydroxytryptamine Receptor 1A in the Portal Vein to Decrease Portal Hypertension
期刊论文
OAI收割
GASTROENTEROLOGY, 2024, 卷号: 167, 期号: 5, 页码: 993-1007
作者:
Zhu, Chang-Peng
;
Liu, Shu-Qing
;
Wang, Ke-Qi
;
Xiong, Hai-Lin
;
Aristu-Zabalza, Peio
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/04
Portal Hypertension
Portal Vein Smooth Muscle Cells
5-Hydroxytryptamine
HTR1A
Alverine
N-terminus GTPase domain of the cytoskeleton protein FtsZ plays a critical role in its adaptation to high hydrostatic pressure
期刊论文
OAI收割
FRONTIERS IN MICROBIOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Cui, Xue-Hua
;
Wei, Yu-Chen
;
Li, Xue-Gong
;
Qi, Xiao-Qing
;
Wu, Long-Fei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/10/21
obligate piezophile
cell division
cytoskeleton
FtsZ
high hydrostatic pressure
GTPase domain
Discovery of a novel BTK inhibitor S-016 and identification of a new strategy for the treatment of lymphomas including BTK inhibitor-resistant lymphomas
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2024/07/12
diffuse large B-cell lymphoma
BTK inhibitors
drug resistance
BTK C481F
BTK A428D
SYHA1813
Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
期刊论文
OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:
Bian, Yi-cong
;
Meng, Jian
;
Hu, Tao
;
Ma, Sheng
;
Huang, Chen-rong
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/05/22
HSK7653
long-acting dipeptidyl peptidase-4 inhibitor
mass balance
metabolism
pharmacokinetics
radiolabelled
Comprehensive HRMS Screening and Risk Assessments of Aristolochic Acid Analogues in Asari Radix et Rhizoma and Related Commercial Health Products
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2024, 卷号: 72, 期号: 13, 页码: 7438-7456
作者:
Hu, Yun-shu
;
Zhang, Jian-qing
;
Wei, Wen-long
;
Yang, Huan-ya
;
Sha, Fei
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/07
aristolochic acid analogues(AAAs)
Asari Radix et Rhizoma
identification
quantification
toxicity