中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-46
作者:
Ling-Chu Chang
;
Hui-Yi Lin
;
Meng-Tung Tsai
;
Ruey-Hwang Chou
;
Fang-Yu Lee
  |  
收藏
  |  
浏览/下载:293/0
  |  
提交时间:2017/07/24
Yc-1
Triple-negative Breast Cancer
Erk
Ezh2
C-cbl
Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:
Chen, Jiexuan
;
Wu, Mingfei
;
Mo, Jun
;
Hong, Ju
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10
作者:
Yu, Qian
;
Gao, Lixin
;
Xu, Linhao
;
Han, Yubing
;
Cao, Yu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/11
Chiral Nanostructured Ag Films for Multicarbon Products from CO
2
Electroreduction
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 卷号: 146
作者:
Zhang, Wanning
;
Ai, Jing
;
Ouyang, Tianwei
;
Yu, Lu
;
Liu, Aokun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/11/20
Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 28
作者:
Duan, Haiting
;
Zhang, Jingyu
;
Gui, Renzhao
;
Lu, Yang
;
Pang, Ao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/20
Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 21
作者:
Lu, Yang
;
Gao, Jian
;
Wang, Peipei
;
Chen, Haifeng
;
He, Xinjun
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/07/12
Hepatocellular carcinoma
Ubiquitin-specific protease 10
Deubiquitination
Selectivity
Cryo-EM structure of human HCN3 channel and its regulation by cAMP
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 卷号: 300, 期号: 6, 页码: 10
作者:
Yu, Bo
;
Lu, Qiuyuan
;
Li, Jian
;
Cheng, Xinyu
;
Hu, Han
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/11
Metabolomics revealed more deleterious toxicity induced by the combined exposure of ammonia and nitrite on
Ruditapes
philippinarum
compared to single exposure
期刊论文
OAI收割
MARINE ENVIRONMENTAL RESEARCH, 2024, 卷号: 196, 页码: 11
作者:
Cong, Ming
;
Li, Zhaoshun
;
Che, Yu
;
Li, Yuanmei
;
Tian, Wenwen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/10/24
Ammonia
Nitrite
Ruditapes philippinarum
Toxicity
Metabolomics
Metabolomics revealed more deleterious toxicity induced by the combined exposure of ammonia and nitrite on
Ruditapes
philippinarum
compared to single exposure
期刊论文
OAI收割
MARINE ENVIRONMENTAL RESEARCH, 2024, 卷号: 196, 页码: 11
作者:
Cong, Ming
;
Li, Zhaoshun
;
Che, Yu
;
Li, Yuanmei
;
Tian, Wenwen
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/05/23
Ammonia
Nitrite
Ruditapes philippinarum
Toxicity
Metabolomics