中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共65条,第1-10条 帮助

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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文  OAI收割
出版物, 3111, 期号: 0, 页码: 1-46
作者:  
Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee
  |  收藏  |  浏览/下载:259/0  |  提交时间:2017/07/24
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:  
Wang, Xiaomin;  Xu, Jun;  Sun, Yiming;  Cao, Siyuwei;  Zeng, Hanlin
  |  收藏  |  浏览/下载:24/0  |  提交时间:2023/10/17
Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:  
Yu, Lei;  Wang, Ya-fang;  Xiao, Jian;  Shen, Qian-qian;  Chi, Shuai-shuai
  |  收藏  |  浏览/下载:11/0  |  提交时间:2023/10/17
Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7629-7644
作者:  
Zhang, Yi;  Yang, Hong;  Li, Bingbing;  Li, Jiayi;  Li, Huaxuan
  |  收藏  |  浏览/下载:20/0  |  提交时间:2023/10/17
Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer 期刊论文  OAI收割
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 8, 页码: 15
作者:  
Wang, Ya-fang;  Yu, Lei;  Hu, Zong-long;  Fang, Yan-fen;  Shen, Yan-yan
  |  收藏  |  浏览/下载:18/0  |  提交时间:2022/11/11
GSK3 beta palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axis 期刊论文  OAI收割
ONCOGENESIS, 2022, 卷号: 11
作者:  
Zhao, Chenggang;  Yu, Huihan;  Fan, Xiaoqing;  Niu, Wanxiang;  Fan, Junqi
  |  收藏  |  浏览/下载:14/0  |  提交时间:2022/12/23
Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3K alpha inhibitors in oesophageal squamous cell carcinoma 期刊论文  OAI收割
CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 卷号: 12, 期号: 5, 页码: 17
作者:  
Xing, Hui;  Gao, Mengshi;  Wang, Yuxiang;  Zhang, Xu;  Shi, Jiajie
  |  收藏  |  浏览/下载:47/0  |  提交时间:2022/08/16
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文  OAI收割
LEUKEMIA, 2022
作者:  
Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng
  |  收藏  |  浏览/下载:68/0  |  提交时间:2022/02/14
Discovery of IHMT-EZH2-115 as a Potent and Selective Enhancer of Zeste Homolog 2 (EZH2) Inhibitor for the Treatment of B-Cell Lymphomas 期刊论文  OAI收割
J. Med. Chem., 2021
作者:  
Qi S(亓爽)
  |  收藏  |  浏览/下载:11/0  |  提交时间:2021/12/09
BPA's transgenerational disturbance to transcription of ovarian steroidogenic genes in rare minnow Gobiocypris rarus via DNA and histone methylation 期刊论文  OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 762, 页码: 11
作者:  
Zhu, Long;  Liu, Yan;  Xue, Xue;  Yuan, Cong;  Wang, Zaizhao
  |  收藏  |  浏览/下载:22/0  |  提交时间:2021/04/21