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浏览/检索结果: 共15条，第1-10条 帮助

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Structure-Based Design and Discovery of a Potent and Cell-Active LC3A/B Covalent Inhibitor 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 14, 页码: 12184-12204
作者:  Zhou, Zhenfei;  Huang, Siqi;  Fan, Shijie;  Li, Xueyuan;  Wang, Chengyu
  |  收藏  |  浏览/下载：3/0  |  提交时间：2024/08/22
Uncovering PROTAC Sensitivity and Efficacy by Multidimensional Proteome Profiling: A Case for STAT3 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4804-4818
作者:  Suo, Yuying;  Du, Daohai;  Chen, Chao;  Zhu, Hongwen;  Wang, Xiongjun
  |  收藏  |  浏览/下载：19/0  |  提交时间：2024/05/07
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region 期刊论文  OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942
作者:  Jiang, Hao;  Zu, Shijia;  Lu, Yu;  Sun, Zhongya;  Adeerjiang, Akejiang
  |  收藏  |  浏览/下载：24/0  |  提交时间：2024/03/27
The discovery of a non-competitive GOT1 inhibitor, hydralazine hydrochloride, via a coupling reaction-based high-throughput screening assay 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 73, 页码: 6
作者:  Wu, Qiqi;  Sun, Zhongya;  Chen, Zhifeng;  Liu, Jingqiu;  Ding, Hong
  |  收藏  |  浏览/下载：72/0  |  提交时间：2022/08/30
Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1) 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 3, 页码: 2174-2190
作者:  Liu, Liping;  Zhu, Rui;  Li, Jiacheng;  Pei, Yuan;  Wang, Shuangshuang
  |  收藏  |  浏览/下载：38/0  |  提交时间：2022/08/16
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
  |  收藏  |  浏览/下载：96/0  |  提交时间：2021/08/17
Discovery and characterization of a novel glucose-6-phosphate dehydrogenase (G6PD) inhibitor via high-throughput screening 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 40, 页码: 127905
作者:  Luo, Zhongyuan;  Du, Daohai;  Liu, Yanjun;  Lu, Tian;  Liu, Liping
  |  收藏  |  浏览/下载：32/0  |  提交时间：2024/03/21
Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 317-333
作者:  Shao, Jingwei;  Zhu, Kongkai;  Du, Daohai;  Zhang, Yuanyuan;  Tao, Hongrui
  |  收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01
Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 867-876
作者:  Zhang, Rukang;  Wang, Jiang;  Zhao, Liang;  Liu, Shien;  Du, Daohai
  |  收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08
developmentofahighthroughputfluorescencepolarizationassayforthediscoveryofezh2eedinteractioninhibitors 期刊论文  OAI收割
actapharmacologicasinica, 2018, 卷号: 39, 期号: 2, 页码: 302
作者:  Zhu Maorong;  Du Daohai;  Hu Junchi;  Li Lianchun;  Liu Jingqiu
  |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01