机构

• 上海药物研究所 [27]
• 烟台海岸带研究所 [5]
• 广州地球化学研究所 [4]
• 水生生物研究所 [3]
• 新疆理化技术研究所 [2]
• 生物物理研究所 [1]
• 更多

采集方式

• OAI收割 [48]

内容类型

• 期刊论文 [48]

发表日期

• 2024 [5]
• 2023 [7]
• 2022 [4]
• 2021 [3]
• 2020 [4]
• 2019 [5]
• 更多

学科主题

• Microbiolo... [2]
• Cell Biolo... [1]
• Chemistry [1]
• Genetics &... [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共48条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13 作者:  Zhang, Qian   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/02/28 Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 112, 页码: 5 作者:  Shen, Wen;  Chen, Xinyao;  Zhou, Liping;  Cheng, Yan;  Zhang, Yan   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/10/21 COVID-19  SARS-CoV-2 3CL pro inhibitor  Drug design  Antiviral activities   Graph Structure Aware Contrastive Multi-View Clustering 期刊论文  OAI收割 IEEE TRANSACTIONS ON BIG DATA, 2024, 卷号: 10, 期号: 3, 页码: 260-274 作者:  Chen, Rui;  Tang, Yongqiang;  Cai, Xiangrui;  Yuan, Xiaojie;  Feng, Wenlong   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/07/04 Correlation  Semantics  Big Data  Representation learning  Data models  Data mining  Analytical models  Contrastive learning  deep representation  graph embedding  multi-view clustering   Hygroscopic Properties of Plateau Surface Salts: Insights from Chemical Composition and Isotope Signatures 期刊论文  OAI收割 ACS EARTH AND SPACE CHEMISTRY, 2024, 卷号: 8, 期号: 5, 页码: 1111-1121 作者:  Hao, Yuxin;  Qiu, Yuhe;  Li, Jun;  Liu, Wanyu;  Chen, Lanxiadi   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/09/13 hygroscopicity  salt evaporites  geochemicalisotopes  sulfur  chlorine  atmosphere   Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4855-4869 作者:  Gu, Chenming;  Liu, Jiayuan;  Qian, Fei;  Yu, Wenchao;  Huang, Doudou   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/05/07 Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids 期刊论文  OAI收割 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2023, 卷号: 185, 页码: 13-25 作者:  Zhao, Chengcheng;  Jiang, Xiangrui;  Peng, Liyuan;  Zhang, Yan;  Li, Huihui   |  收藏  |  浏览/下载：40/0  |  提交时间：2024/01/16 Heart failure  Hypertrophy  Epoxyeicosatrienoic acids  Soluble epoxide hydrolase   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：35/0  |  提交时间：2024/03/25 Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12 作者:  Zhu, Mengwei;  Fu, Tiantian;  You, Mengyuan;  Cao, Junyuan;  Yang, Hanxi   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 COVID-19  SARS-CoV-2  3CL protease  Nirmatrelvir  Peptidomimetic inhibitors   Tracing the origin and formation mechanisms of coalbed gas from the Fuxin Basin in China using geochemical and isotopic signatures of the gas and coproduced water 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF COAL GEOLOGY, 2023, 卷号: 267, 页码: 12 作者:  Chen, Xiangrui;  Wang, Yunpeng;  Tao, Mingxin;  Zhou, Zheng;  He, Zhihua   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/08/22 Microbial coalbed gas  Coproduction water  CO 2 dissolution  Isotope fractionation  Fuxin Basin   Increased Soluble Epoxide Hydrolase Activity Positively Correlates with Mortality in Heart Failure Patients with Preserved Ejection Fraction: Evidence from Metabolomics 期刊论文  OAI收割 Phenomics, 2023, 卷号: 3, 期号: 1, 页码: 34-49 作者:  Peng, Liyuan   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/03/26