中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [19]
上海硅酸盐研究所 [6]
金属研究所 [5]
半导体研究所 [4]
合肥物质科学研究院 [2]
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期刊论文 [41]
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2025 [1]
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Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:
Chen, Jiexuan
;
Wu, Mingfei
;
Mo, Jun
;
Hong, Ju
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
Discovery of N-Benzylpiperidinol derivatives as USP7 inhibitors against Hematology
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 13
作者:
Pan, Youlu
;
Chen, Haifeng
;
Fu, Jingfeng
;
Zhang, Jingyu
;
Wang, Peipei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/10/21
Single-cell sequencing reveals the heterogeneity of pancreatic neuroendocrine tumors under genomic instability and histological grading
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 9, 页码: 18
作者:
Ye, Zeng
;
Zhou, Yan
;
Hu, Yuheng
;
Li, Qiang
;
Xu, Zijin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/11/05
tumor cells
CNV neutral tumor cells
neuroendocrine cells
profile
Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 28
作者:
Duan, Haiting
;
Zhang, Jingyu
;
Gui, Renzhao
;
Lu, Yang
;
Pang, Ao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/20
Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 21
作者:
Lu, Yang
;
Gao, Jian
;
Wang, Peipei
;
Chen, Haifeng
;
He, Xinjun
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/07/12
Hepatocellular carcinoma
Ubiquitin-specific protease 10
Deubiquitination
Selectivity
Extinction of microgravity partially premixed flame aboard the Chinese Space Station
期刊论文
OAI收割
PROCEEDINGS OF THE COMBUSTION INSTITUTE, 2024, 卷号: 40, 期号: 1-4, 页码: 7
作者:
Wen, Yuzhe
;
Li, Longfei
;
Li, Xingxian
;
Luo, Lei
;
Chen, Tao
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/23
Partially premixed flame
Non-premixed flame
Radiation
Microgravity
Extinction
Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15
作者:
Zhu, Cheng-Liang
;
Luo, Xiaomin
;
Tian, Tian
;
Rao, Zijian
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/16
AKT
Protein kinase B
PROTAC
Chemical degrader
Rational design
Effects of wet oxidation on residual stress variation of SiCf/SiC composites
期刊论文
OAI收割
CERAMICS INTERNATIONAL, 2022, 卷号: 48, 期号: 8, 页码: 11702-11708
作者:
Wu, Huiyang
;
Guo, Feiyu
;
Yin, Handi
;
Yang, Xinxin
;
Chen, Xiaowu
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/06/15
SiCf/SiC composites
Residual stress
Wet oxidation
Raman spectroscopy
Microstructural and mechanical evolution of SiCf/SiC composites in wet oxygen atmosphere above 1000 degrees C
期刊论文
OAI收割
CERAMICS INTERNATIONAL, 2022, 卷号: 48, 期号: 6, 页码: 8473-8480
作者:
Guo, Feiyu
;
Chen, Xiaowu
;
Cheng, Guofeng
;
Wu, Huiyang
;
Zhou, Haijun
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/06/15
Wet-oxygen
SiCf/SiC
Residual stress
Bending strength
Raman spectra
Discovery of seneciobipyrrolidine derivatives for the amelioration of glucose homeostasis disorders through 4E-BP1/Akt/AMPK signaling activation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 228, 页码: 25
作者:
Che, Jinxin
;
Ma, Canliang
;
Lu, Jialiang
;
Chen, Binhui
;
Shi, Qiuqiu
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/06/15
Seneciobipyrrolidine
Phenotypic screening
Glucose homeostasis
Proteomic analysis
L6 myotubes
4E-BP1