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浏览/检索结果: 共5063条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24 作者:  Li, Na;  Wang, Linlin;  Hu, Xinyuan;  Xu, Haiyan;  Yang, Bowen   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Voltage-gated sodium channel 1.8  Conformational restriction  Pharmacokinetic  Structure-activity relationship  Analgesic   Deciphering multi-media occurrence and anthropogenic drivers of potentially toxic elements in a rapidly urbanized estuary: A neural network-enhanced source apportionment 期刊论文  OAI收割 MARINE POLLUTION BULLETIN, 2025, 卷号: 218, 页码: 118178 作者:  Wang, Weili;  Lin, Yuhong;  Pan, Zhong;  Liu, Yang;  Wang, Lingqing   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/07/18 Bioaccumulation  Pollution characteristics  Multimedia  Ecological risk  Source   Immunosuppressive nitrogen-containing triterpenoid saponins from Mussaenda erosa and the therapeutic efficacy of heinsiagenin A in a murine lupus erythematosus model 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 11 作者:  Xu, Yidan;  Xiang, Mai;  Chang, Yuan;  Chen, Zhenhua;  Zhang, Rujun   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Mussaenda erosa  Nitrogen-containing triterpenoid saponins  Immunosuppressive activity  Autoimmune diseases  Heinsiagenin A   EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow 期刊论文  OAI收割 ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1 作者:  Jiang, Shuai-Qing;  Xu, Dong;  Hoof, Agnes P. C. van;  Lei, Wei-Hua;  Liu, Yuan   |  收藏  |  浏览/下载：21/0  |  提交时间：2025/07/28 Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20 作者:  Zheng, Fuqiang;  Hu, Zhengtao;  Chen, Hai;  Cheng, Jiaxin;  Hou, Qiongqiong   |  收藏  |  浏览/下载：23/0  |  提交时间：2025/06/23 Heterocycle-fused phenylcyclohexylamines  Multi-target antagonists  NMDAR  Monoamine transporter  Antidepressants   Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins 期刊论文  OAI收割 SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7 作者:  Cao, Zhen;  Aharonian, F.;  Axikegu;  Bai, Y. X.;  Bao, Y. W.   |  收藏  |  浏览/下载：33/0  |  提交时间：2025/06/10 gamma rays  cosmic rays  supernova remnant  young massive cluster  pulsar   Engineering of Sono-Activatable Immunogels for Immunometabolism Disorder Normalization Therapy of Breast Cancer 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 26, 页码: 22412-22426 作者:  Guo, Yu;  Pan, Jiaxing;  Wang, Junjue;  Zhang, Huijuan;  Yang, Wenfang   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 15 作者:  Xu, Yali;  Hu, Hao;  Ran, Yu;  Zhao, Wensi;  Guo, An-Di   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Chemoproteomics  Molecular glue degraders  Photo-crosslinking  Protein-protein interactions  Targeted protein degradation   Advancing active compound discovery for novel drug targets: insights from AI-driven approaches 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12 作者:  Wang, Xing-you;  Chen, Yang;  Li, Yu-fan;  Wei, Chao-yang;  Liu, Meng-ya   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/08/20 AI-driven drug discovery  novel drug targets  molecular design  ligand exploration  phenotypic drug discovery  undruggable targets   Research on the effects and related mechanisms of geomagnetic storm on depression 期刊论文  OAI收割 BRAIN RESEARCH BULLETIN, 2025, 卷号: 226 作者:  Wu, Hui;  Yang, Yuan;  Chang, Weiyu;  Chen, Xinli;  Yang, Shiqi   |  收藏  |  浏览/下载：24/0  |  提交时间：2025/06/04 Depression  Geomagnetic storms  Melatonin