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浏览/检索结果: 共14条，第1-10条 帮助

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Discovery of Covalent and Cell-Active ALKBH5 Inhibitors with Potent Antileukemia Effects In Vivo 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 9
作者:  Wu, Hengbo;  Lai, Gan-Qiang;  Cheng, Ruixiang;  Huang, Hui;  Wang, Ju
  |  收藏  |  浏览/下载：0/0  |  提交时间：2025/04/24
Fracture behavior and deformation-induced structure changes of a Ti-based metallic glass using micro-sized cantilevers 期刊论文  OAI收割
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING, 2022, 卷号: 833, 页码: 9
作者:  Chu, Qiaoling;  Cao, Qilu;  Zhu, Xiaofei;  Zhang, Min;  Zhu, Zhengwang
  |  收藏  |  浏览/下载：34/0  |  提交时间：2022/07/01
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML) 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
作者:  Lu, Tingting;  Cao, Jiangyan;  Zou, Fengming;  Li, Xixiang;  Wang, Aoli
  |  收藏  |  浏览/下载：64/0  |  提交时间：2021/04/26
Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia 期刊论文  OAI收割
HAEMATOLOGICA, 2021, 卷号: 106
作者:  Wang, Aoli;  Hu, Chen;  Chen, Cheng;  Liang, Xiaofei;  Wang, Beilei
  |  收藏  |  浏览/下载：73/0  |  提交时间：2021/04/26
Network-based analysis with primary cells reveals drug response landscape of acute myeloid leukemia 期刊论文  OAI收割
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 393
作者:  Chen, Cheng;  Wang, Li;  Li, Lili;  Wang, Aoli;  Huang, Tao
  |  收藏  |  浏览/下载：61/0  |  提交时间：2020/11/26
Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文  OAI收割
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping
  |  收藏  |  浏览/下载：88/0  |  提交时间：2019/11/27
Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:  Liang, Xiaofei;  Wang, Beilei;  Chen, Cheng;  Wang, Aoli;  Hu, Chen
  |  收藏  |  浏览/下载：44/0  |  提交时间：2020/05/21
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
  |  收藏  |  浏览/下载：54/0  |  提交时间：2019/01/11
Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 20, 页码: 8407-8424
作者:  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Wu, Hong;  Qi, Ziping
  |  收藏  |  浏览/下载：56/0  |  提交时间：2019/06/17
The star formation history of low-mass disk galaxies: A case study of NGC300 期刊论文  OAI收割
ASTRONOMY & ASTROPHYSICS, 2016, 卷号: 585, 页码: A20
Kang, XY (Kang, Xiaoyu); Zhang, FH (Zhang, Fenghui); Chang, RX (Chang, Ruixiang); Wang, L (Wang, Lang); Cheng, LT (Cheng, Liantao)
收藏  |  浏览/下载：19/0  |  提交时间：2016/11/24