中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共1253条,第1-10条 帮助

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The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文  OAI收割
出版物, 2111, 页码: 1-44
作者:  
1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
  |  收藏  |  浏览/下载:220/0  |  提交时间:2017/07/24
Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:  
Hao, Bing-bing;  Ma, Ke;  Xu, Jun-yu;  Fan, Ru-feng;  Zhao, Wen-si
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/03/25
Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17
作者:  
Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/02/27
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:  
Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/03/25
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:  
Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke
  |  收藏  |  浏览/下载:9/0  |  提交时间:2024/02/27
Structure-based optimization of indoline-containing compounds as second generation inhibitors of NF-KB-inducing kinase (NIK) 期刊论文  OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1295, 页码: 19
作者:  
Cheng, Jing;  Yan, Ziqin;  Li, Xinzhi
  |  收藏  |  浏览/下载:8/0  |  提交时间:2023/12/08
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:  
Zhang, Hongjin;  Lin, Guohao;  Jia, Suyun;  Zhang, Ying;  Wu, Jianbo
  |  收藏  |  浏览/下载:5/0  |  提交时间:2024/01/26
Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation 期刊论文  OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13
作者:  
Feng, Dazhi;  Liu, Bo;  Chen, Zhiwei;  Xu, Jinyi;  Geng, Meiyu
  |  收藏  |  浏览/下载:24/0  |  提交时间:2024/02/27
The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus 期刊论文  OAI收割
VIRULENCE, 2023, 卷号: 14, 期号: 1, 页码: 2171641
作者:  
Chen, Feifei;  Di, Hongxia;  Wang, Yanhui;  Peng, Chao;  Chen, Rongrong
  |  收藏  |  浏览/下载:1/0  |  提交时间:2024/03/27
Targeting ST8SIA6-AS1 counteracts KRASG12C inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling 期刊论文  OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:  
Wang, Yafang;  Yao, Mingyue;  Li, Cheng;  Yang, Kexin;  Qin, Xiaolong
  |  收藏  |  浏览/下载:7/0  |  提交时间:2024/01/26