机构

• 上海药物研究所 [11]
• 金属研究所 [3]
• 大连化学物理研究所 [2]
• 寒区旱区环境与工程研... [1]
• 上海营养与健康研究所 [1]

采集方式

• OAI收割 [17]
• iSwitch采集 [1]

内容类型

• 期刊论文 [18]

发表日期

• 2025 [1]
• 2023 [2]
• 2022 [2]
• 2021 [1]
• 2020 [2]
• 2019 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共18条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679 作者:  Jin, Yuheng;  Qi, Xuxin;  Yu, Xiaoli;  Cheng, Xirui;  Chen, Boya   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/06/23 HDAC7  PROTAC  Selectivity  Hematologic malignancies  Non-enzymatic function   Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：34/0  |  提交时间：2024/02/19 Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 22, 页码: 15269-15287 作者:  Hu, Linghao;  Li, Huiyun;  Qin, Junlin;  Yang, Dan;  Liu, Jieming   |  收藏  |  浏览/下载：53/0  |  提交时间：2024/02/27 Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15 作者:  Zhu, Cheng-Liang;  Luo, Xiaomin;  Tian, Tian;  Rao, Zijian;  Wang, Hanlin   |  收藏  |  浏览/下载：50/0  |  提交时间：2022/08/16 AKT  Protein kinase B  PROTAC  Chemical degrader  Rational design   Mechanisms of Grain Refinement in Direct-Chill Casting 2024 Aluminum Alloy With Intensive Melt Shearing 期刊论文  OAI收割 METALLURGICAL AND MATERIALS TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE, 2022, 页码: 9 作者:  Liu, Xudong;  Zhu, Qingfeng;  Zhu, Cheng;  Zuo, Yubo;  Jiang, Haichang   |  收藏  |  浏览/下载：41/0  |  提交时间：2022/07/01 SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文  OAI收割 CELL RESEARCH, 2021, 页码: 14 作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang   |  收藏  |  浏览/下载：111/0  |  提交时间：2021/08/17 Fatigue properties of titanium alloy custom short stems fabricated by electron beam melting 期刊论文  OAI收割 JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2020, 卷号: 52, 页码: 180-188 作者:  Wang, Liao;  Li, Shujun;  Yan, Mengning;  Cheng, Yubo;  Hou, Wentao   |  收藏  |  浏览/下载：48/0  |  提交时间：2021/02/02 Custom short stem  Titanium alloy  Electron beam melting  Fatigue property   Fatigue properties of titanium alloy custom short stems fabricated by electron beam melting 期刊论文  OAI收割 JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2020, 卷号: 52, 页码: 180-188 作者:  Wang, Liao;  Li, Shujun;  Yan, Mengning;  Cheng, Yubo;  Hou, Wentao   |  收藏  |  浏览/下载：44/0  |  提交时间：2021/02/02 Custom short stem  Titanium alloy  Electron beam melting  Fatigue property   fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85 作者:  Zhan, Wenhu;  Che, Jinxin;  Xu, Lei;  Wu, Yizhe;  Hu, Xiaobei   |  收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01 Pyrazole-thiophene derivatives  Akt inhibitor  Antitumor   Discovery of novel indoleaminopyrimidine NIK inhibitors based on molecular docking-based support vector regression (SVR) model 期刊论文  OAI收割 CHEMICAL PHYSICS LETTERS, 2019, 卷号: 718, 页码: 38-45 作者:  Ye, Qing;  Li, Qiu;  Gao, Anhui;  Ying, Huazhou;  Cheng, Gang   |  收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01