机构

• 上海药物研究所 [13]
• 大连化学物理研究所 [5]
• 宁波材料技术与工程研... [2]
• 计算技术研究所 [1]
• 心理研究所 [1]
• 上海应用物理研究所 [1]
• 更多

采集方式

• OAI收割 [26]

内容类型

• 期刊论文 [25]
• 会议论文 [1]

发表日期

• 2025 [1]
• 2024 [3]
• 2023 [4]
• 2022 [3]
• 2021 [3]
• 2020 [3]
• 更多

学科主题

• Instrument... [1]
• Science & ... [1]
• 物理化学 [1]

筛选

浏览/检索结果: 共26条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21 作者:  Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/12/25 Synthetic lethal  MSI tumors  WRN inhibitors  Triazolo-pyrimidine derivatives   Targeting JMJD1C to selectively disrupt tumor Treg cell fitness enhances antitumor immunity 期刊论文  OAI收割 NATURE IMMUNOLOGY, 2024, 页码: 32 作者:  Long, Xuehui;  Zhang, Sulin;  Wang, Yuliang;  Chen, Jingjing;  Lu, Yanlai   |  收藏  |  浏览/下载：38/0  |  提交时间：2024/03/25 Transfer learning enhanced graph neural network for aldehyde oxidase metabolism prediction and its experimental application 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 2, 页码: 623-634 作者:  Xiong, Jiacheng;  Cui, Rongrong;  Li, Zhaojun;  Zhang, Wei;  Zhang, Runze   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/05/07 Drug metabolism  Aldehyde oxidase  Transfer learning  Graph neural network  Kinase inhibitor   Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/02/27 Sequence-based drug design as a concept in computational drug design 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21 作者:  Chen, Lifan;  Fan, Zisheng;  Chang, Jie;  Yang, Ruirui;  Hou, Hui   |  收藏  |  浏览/下载：43/0  |  提交时间：2023/10/17 Multi-source underwater DOA estimation using PSO-BP neural network based on high-order cumulant optimization 期刊论文  OAI收割 CHINA COMMUNICATIONS, 2023, 页码: 18 作者:  Chen, Haihua;  Zhang, Jingyao;  Jiang, Bin;  Cui, Xuerong;  Zhou, Rongrong   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/12/04 Direction-of-arrival estimation  Estimation  Neural networks  Mathematical models  Training  Covariance matrices  Biological neural networks  particle swarm optimization (PSO) algorithm  PSO-BP neural network  gaussian colored noise  multiple sources  higher-order cumulant   Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214 作者:  Zhou, Zehui;  Zhou, Guizhen;  Zhou, Chuan;  Fan, Zisheng;  Cui, Rongrong   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/03/27 Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3327-3347 作者:  Shan, Bin;  Hou, Hui;  Zhang, Keke;  Li, Rui;  Shen, Chang   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/03/27 Obsessive-compulsive disorder in Chinese methamphetamine patients: Prevalence, demographics, and clinical characteristics 期刊论文  OAI收割 AMERICAN JOURNAL ON ADDICTIONS, 2022, 页码: 5 作者:  Liu, Siying;  Wan, Jiaxue;  Liang, Qilin;  Tian, Yang;  Fan, Fusheng   |  收藏  |  浏览/下载：30/0  |  提交时间：2023/01/16 Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 3923-3942 作者:  Zhou, Chuan;  Fan, Zisheng;  Zhou, Zehui;  Li, Yupeng;  Cui, Rongrong   |  收藏  |  浏览/下载：54/0  |  提交时间：2022/06/15