机构

• 上海药物研究所 [25]
• 武汉病毒研究所 [5]
• 金属研究所 [2]
• 力学研究所 [1]
• 地理科学与资源研究所 [1]
• 成都山地灾害与环境研... [1]
• 更多

采集方式

• OAI收割 [31]
• iSwitch采集 [5]

内容类型

• 期刊论文 [36]

发表日期

• 2025 [4]
• 2024 [6]
• 2023 [3]
• 2022 [4]
• 2021 [4]
• 2020 [6]
• 更多

学科主题

筛选

浏览/检索结果: 共36条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Discovery of 3-(Fluoro-imidazolyl)pyridazine Derivatives as Potent STING Agonists with Antitumor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 9864-9885 作者:  Hou, Hui;  Zhou, Jingyi;  Sui, Qibang;  Zhang, Changfa;  Su, Zhaoming   |  收藏  |  浏览/下载：11/0  |  提交时间：2025/07/25 Residue-Selective Inhibitors Discovery via Covalent DNA-Encoded Chemical Libraries with Diverse Warheads 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 18, 页码: 15469-15481 作者:  Wu, Xinyuan;  Pan, Jiayi;  Fan, Rufeng;  Zhang, Yiwei;  Wang, Chao   |  收藏  |  浏览/下载：23/0  |  提交时间：2025/06/23 Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14 作者:  Wu, Xinyuan;  Li, Shunyao;  Liang, Ting;  Yu, Qing;  Zhang, Yiwei   |  收藏  |  浏览/下载：22/0  |  提交时间：2025/06/23 Activity-based protein profiling data  Covalent DNA-encoded chemical library  Covalent ligand selection  Lysine-targeting covalent inhibitors   Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21 作者:  Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/12/25 Synthetic lethal  MSI tumors  WRN inhibitors  Triazolo-pyrimidine derivatives   Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 14 作者:  Wang, Xudong;  Xiong, Liwei;  Zhu, Ying;  Liu, Sixiu;  Zhao, Wenfeng   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/12/25 Enhancing the Predictive Power of Machine Learning Models through a Chemical Space Complementary DEL Screening Strategy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 12 作者:  Suo, Yanrui;  Qian, Xu;  Xiong, Zhaoping;  Liu, Xiaohong;  Wang, Chao   |  收藏  |  浏览/下载：117/0  |  提交时间：2024/11/26 Interface healing mechanism of fine-grained Ni-Co-based superalloy during hot-compression bonding 期刊论文  OAI收割 JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2024, 卷号: 173, 页码: 45-53 作者:  Ren, Shaofei;  Bai, Xiaolong;  Liu, Sheng;  Sun, Mingyue;  Xu, Bin   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/01/08 Hot-compression bonding  Ni-Co-based superalloy  Discontinuous dynamic recrystallization  Heterogeneous epitaxial recrystallization   Targeting JMJD1C to selectively disrupt tumor Treg cell fitness enhances antitumor immunity 期刊论文  OAI收割 NATURE IMMUNOLOGY, 2024, 页码: 32 作者:  Long, Xuehui;  Zhang, Sulin;  Wang, Yuliang;  Chen, Jingjing;  Lu, Yanlai   |  收藏  |  浏览/下载：63/0  |  提交时间：2024/03/25 Transfer learning enhanced graph neural network for aldehyde oxidase metabolism prediction and its experimental application 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 2, 页码: 623-634 作者:  Xiong, Jiacheng;  Cui, Rongrong;  Li, Zhaojun;  Zhang, Wei;  Zhang, Runze   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/05/07 Drug metabolism  Aldehyde oxidase  Transfer learning  Graph neural network  Kinase inhibitor   Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：36/0  |  提交时间：2024/02/27