中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共104条,第1-10条 帮助

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Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors 期刊论文  OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13
作者:  
Tang, Mingze;  Zhou, Xuan;  Shen, Qianqian;  Fang, Chen;  Peng, Xia
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/08/22
Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors 期刊论文  OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 16
作者:  
An, Yuxiang;  Peng, Xia;  Wang, Tianchen;  Liu, Kaiyuan;  Feng, Dazhi
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/12/25
Design, synthesis, and structure-activity relationship studies of 6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole derivatives as necroptosis inhibitors 期刊论文  OAI收割
RSC MEDICINAL CHEMISTRY, 2024, 卷号: 15, 期号: 7, 页码: 2514-2526
作者:  
Jin, Zechen;  Dai, Yang;  Ji, Yinchun;  Peng, Xia;  Duan, Wenhu
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/08/20
Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors 期刊论文  OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 21
作者:  
Lan, Yaohan;  Ji, Yinchun;  Peng, Xia;  Duan, Wenhu;  Geng, Meiyu
  |  收藏  |  浏览/下载:1/0  |  提交时间:2024/08/22
Design, synthesis, and evaluation of thiazolecarboxamide derivatives as stimulator of interferon gene inhibitors 期刊论文  OAI收割
MOLECULAR DIVERSITY, 2024, 页码: 27
作者:  
  |  收藏  |  浏览/下载:15/0  |  提交时间:2024/05/31
A Novel IRAK4 Inhibitor DW18134 Ameliorates Peritonitis and Inflammatory Bowel Disease 期刊论文  OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 8, 页码: 17
作者:  
Huang, Yuqing;  Ning, Yi;  Chen, Zhiwei;  Song, Peiran;  Tang, Haotian
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/05/31
A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy 期刊论文  OAI收割
CANCER COMMUNICATIONS, 2024, 页码: 5
作者:  
Liu, Yingqiang;  Tong, Linjiang;  Zhang, Mengge;  Zhang, Qi;  Liu, Qiupei
  |  收藏  |  浏览/下载:37/0  |  提交时间:2024/03/13
Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17
作者:  
Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu
  |  收藏  |  浏览/下载:28/0  |  提交时间:2024/02/27
Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation 期刊论文  OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13
作者:  
Feng, Dazhi;  Liu, Bo;  Chen, Zhiwei;  Xu, Jinyi;  Geng, Meiyu
  |  收藏  |  浏览/下载:46/0  |  提交时间:2024/02/27
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:  
Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong
  |  收藏  |  浏览/下载:23/0  |  提交时间:2024/01/26