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浏览/检索结果: 共21条，第1-10条 帮助

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Discovery of Novel Tridentate Alkenyl Diacid Derivatives as Potent ATP Citrate Lyase Inhibitors for the Treatment of Hepatocellular Carcinoma 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 15, 页码: 15598-15616
作者:  Yang, Yurou;  Zhai, Jimao;  Wang, Fan;  Song, Gaolei;  Xu, Honghong
  |  收藏  |  浏览/下载：0/0  |  提交时间：2025/09/09
Design, Synthesis, and Pharmacological Evaluation of Isoindoline Analogues as New HPK1 Inhibitors 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 23, 页码: 16201-16221
作者:  Xie, Chenghu;  Liu, Bo;  Song, Zilan;  Yang, Ye;  Dai, Mengdi
  |  收藏  |  浏览/下载：102/0  |  提交时间：2024/02/27
Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17
作者:  Zeng, Yanping;  Xiao, Jian;  Xu, Yuanxin;  Wei, Fan;  Tian, Lina
  |  收藏  |  浏览/下载：49/0  |  提交时间：2023/10/17
The HDAC inhibitor GCJ-490A suppresses c-Met expression through IKK? and overcomes gefitinib resistance in non-small cell lung cancer 期刊论文  OAI收割
CANCER BIOLOGY & MEDICINE, 2022, 卷号: 19, 期号: 8, 页码: 1172-1192
作者:  He, Ting;  Gao, Yinglei;  Fang, Yanfen;  Zhang, Yangming;  Zhang, Shuwei
  |  收藏  |  浏览/下载：68/0  |  提交时间：2024/03/21
F-18-FDG PET as an imaging biomarker for the response to FGFR-targeted therapy of cancer cells via FGFR-initiated mTOR/HK2 axis 期刊论文  OAI收割
THERANOSTICS, 2022, 卷号: 12, 期号: 14, 页码: 6395-6408
作者:  Jiang, Yuchen;  Zeng, Qinghe;  Jiang, Qinghui;  Peng, Xia;  Gao, Jing
  |  收藏  |  浏览/下载：75/0  |  提交时间：2022/12/13
Design, Synthesis, and Biological Evaluation of HSP90 Inhibitor-SN38 Conjugates for Targeted Drug Accumulation 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 10, 页码: 5421-5441
作者:  Zhu, Shulei;  Shen, Qianqian;  Gao, Yinglei;  Wang, Lei;  Fang, Yanfen
  |  收藏  |  浏览/下载：47/0  |  提交时间：2020/12/24
Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and and in vivo study 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 351-368
作者:  Wei, Peng;  Liu, Bo;  Wang, Ruifeng;  Gao, Yinglei;  Li, Lanlan
  |  收藏  |  浏览/下载：75/0  |  提交时间：2020/07/01
Simultaneous inhibition of PI3K alpha and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer 期刊论文  OAI收割
CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-+
作者:  Wang, Yuxiang;  Li, Xian;  Liu, Xueling;  Chen, Yi;  Yang, Chunhao
  |  收藏  |  浏览/下载：55/0  |  提交时间：2020/07/01
PI3K alpha  CDK4/6  KRAS  NSCLC  CYH33  
Simultaneous inhibition of PI3Kα and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer 期刊论文  OAI收割
CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-83
作者:  Wang, Yuxiang;  Li, Xian;  Liu, Xueling;  Chen, Yi;  Yang, Chunhao
  |  收藏  |  浏览/下载：48/0  |  提交时间：2024/03/21
PI3K alpha  CDK4/6  KRAS  NSCLC  CYH33  
Simultaneous inhibition of PI3Kα and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer 期刊论文  OAI收割
Cancer Biology and Medicine, 2019, 卷号: 16, 期号: 1, 页码: 66
作者:  Wang Yuxiang;  Li Xian;  Liu Xueling;  Chen Yi;  Yang Chunhao
  |  收藏  |  浏览/下载：65/0  |  提交时间：2020/12/24
PI3Kα  CDK4/6  KRAS  NSCLC  CYH33