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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [231]
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期刊论文 [237]
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Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13
作者:
Tang, Mingze
;
Zhou, Xuan
;
Shen, Qianqian
;
Fang, Chen
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/08/22
Receptor -interacting protein kinase 1
Histone deacetylases
Inhibitor
Molecular dynamics (MD) simulation
ADMET analysis
Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 16
作者:
An, Yuxiang
;
Peng, Xia
;
Wang, Tianchen
;
Liu, Kaiyuan
;
Feng, Dazhi
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/25
inhibitor
pharmacokinetic study
pyridazin-4-one
receptor-interacting protein kinase 1
selectivity
Sodium oligomannate disrupts the adherence of Rib
high
bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19
作者:
Wang, Xinyi
;
Xie, Zuoquan
;
Yuan, Jie
;
Jin, Enjing
;
Lian, Wen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/16
A DXd/TLR7-Agonist Dual-Conjugate Anti-HER2 ADC Exerts Robust Antitumor Activity Through Tumor Cell Killing and Immune Activation
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2024, 卷号: 23, 期号: 11, 页码: 1639-1651
作者:
Yue, Hangtian
;
Xu, Hui
;
Ma, Lanping
;
Li, Xiyuan
;
Yang, Biyu
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/12/11
Integrated omics profiling reveals systemic dysregulation and potential biomarkers in the blood of patients with neuromyelitis optica spectrum disorders
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 18
作者:
Xie, Zuoquan
;
Zhou, Qinming
;
Hu, Jin
;
He, Lu
;
Meng, Huangyu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/12/11
Neuromyelitis optica spectrum disorders
Blood immune cells phenotyping
Plasma cytokine array
Plasma metabolomics
Biomarker
13,14-seco
seco
withaphysalins from
Physalis
minima
and their inhibitory effects on NLRP3 inflammasome activation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 151, 页码: 12
作者:
Hu, Bintao
;
Peng, Xia
;
Tang, Chunping
;
Geng, Meiyu
;
Yao, Sheng
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/09/26
Physalis minima
NLRP3
Anti-inflammatory
13,14-seco withaphysalin
GV-971 prevents severe acute pancreatitis by remodeling the microbiota-metabolic-immune axis
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 18
作者:
Chen, Xi
;
Chen, Xin
;
Yan, Ding
;
Zhang, Na
;
Fu, Wen
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/02/28
Multi-omics profiling reveals peripheral blood biomarkers of multiple sclerosis: implications for diagnosis and stratification
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 12
作者:
Zhou, Qinming
;
Xie, Zuoquan
;
He, Lu
;
Sun, Guangqiang
;
Meng, Huanyu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/10/21
multiple sclerosis
multi-omics
blood immune phenotyping
proteomic
metabolomic
clinically isolated syndrome
secondary progressive MS
Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 17
作者:
Zhang, Tao
;
Pan, Zilu
;
Gao, Jing
;
Wu, Qingqing
;
Bai, Gang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/10/21
Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 21
作者:
Lan, Yaohan
;
Ji, Yinchun
;
Peng, Xia
;
Duan, Wenhu
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/08/22
autoimmune disease
necroptosis inhibitor
pharmacokinetic profile
receptor interacting protein kinase 1 (RIPK1)
structural optimization