机构

• 上海药物研究所 [238]
• 金属研究所 [4]
• 广州生物医药与健康研... [2]
• 中国科学院大学 [1]
• 海洋研究所 [1]
• 合肥物质科学研究院 [1]
• 更多

采集方式

• OAI收割 [247]
• iSwitch采集 [1]

内容类型

• 期刊论文 [244]
• 会议论文 [4]

发表日期

• 2025 [6]
• 2024 [20]
• 2023 [11]
• 2022 [15]
• 2021 [10]
• 2020 [8]
• 更多

学科主题

• Biochemist... [2]
• Pharmacolo... [2]
• Multidisci... [1]

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浏览/检索结果: 共248条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Discovery of indole derivatives as STING degraders 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 21 作者:  An, Yuxiang;  Zhang, Yan;  Luo, Xin;  Lan, Yaohan;  Geng, Meiyu   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Autoimmune diseases  Degrader  Inflammatory  PROTAC  STING   Structural Optimization of Next-Generation TRK Inhibitors against Acquired Drug Resistance Mutations for the Treatment of Solid Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 11, 页码: 11484-11501 作者:  Xu, Zichao;  Liu, Yueling;  Wang, Peng;  Peng, Xia;  Cheng, Jiawei   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth 期刊论文  OAI收割 MOLECULES, 2025, 卷号: 30, 期号: 10, 页码: 22 作者:  Peng, Xia   |  收藏  |  浏览/下载：16/0  |  提交时间：2025/07/25 pseudolaric acid B  amide derivatives  tumor-associated macrophages  anti-tumor  repolarization   Discovery of Potent STING Inhibitors Bearing a Difluorobenzodioxol Structural Motif as Potent Anti-Inflammatory Agents 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8907-8932 作者:  Shen, Ancheng;  Wang, Xiyuan;  Chen, Qingxuan;  Zhang, Yan;  Wang, Fang   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/05/27 Quantitation of global histone post-translational modifications reveal anti-inflammatory epigenetic mechanisms of liquiritigenin based on the optimized super-SILAC strategy 期刊论文  OAI收割 FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2025, 卷号: 13, 页码: 15 作者:  Liu, Ping;  Zhang, Jun   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/05/27 histone post-translational modifications  super-SILAC  liquiritigenin  inflammation  epigenetics  PPAR   Discovery of a non-nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect 期刊论文  OAI收割 MEDCOMM, 2025, 卷号: 6, 期号: 1, 页码: e70001 作者:  Wang, Xiyuan;  Zhan, Zhengsheng;  Wang, Zhen;  Zhang, Yan;  Zhao, Kaiyan   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/06/04 antitumor  immune memory  innate immunity  STING agonist   Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13 作者:  Tang, Mingze;  Zhou, Xuan;  Shen, Qianqian;  Fang, Chen;  Peng, Xia   |  收藏  |  浏览/下载：28/0  |  提交时间：2024/08/22 Receptor -interacting protein kinase 1  Histone deacetylases  Inhibitor  Molecular dynamics (MD) simulation  ADMET analysis   Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 16 作者:  An, Yuxiang;  Peng, Xia;  Wang, Tianchen;  Liu, Kaiyuan;  Feng, Dazhi   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/12/25 inhibitor  pharmacokinetic study  pyridazin-4-one  receptor-interacting protein kinase 1  selectivity   Sodium oligomannate disrupts the adherence of Ribhigh bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice 期刊论文  OAI收割 CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19 作者:  Wang, Xinyi;  Xie, Zuoquan;  Yuan, Jie;  Jin, Enjing;  Lian, Wen   |  收藏  |  浏览/下载：34/0  |  提交时间：2024/12/16 A DXd/TLR7-Agonist Dual-Conjugate Anti-HER2 ADC Exerts Robust Antitumor Activity Through Tumor Cell Killing and Immune Activation 期刊论文  OAI收割 MOLECULAR CANCER THERAPEUTICS, 2024, 卷号: 23, 期号: 11, 页码: 1639-1651 作者:  Yue, Hangtian;  Xu, Hui;  Ma, Lanping;  Li, Xiyuan;  Yang, Biyu   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/12/11