中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
昆明植物研究所 [16]
上海药物研究所 [13]
大连化学物理研究所 [9]
广州生物医药与健康研... [8]
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期刊论文 [59]
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FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15
作者:
Wen, Ying-quan
;
Zou, Zi-yuan
;
Zhao, Guan-guan
;
Zhang, Meng-jiao
;
Zhang, Yong-xin
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/08/22
MASLD/MASH
FXR
transcriptome
gut-liver axis
agonist
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:
Zhao,Qi
;
Dai,Man-Yun
;
Huang,Ruo-Yue
;
Duan,Jing-Yi
;
Zhang,Ting
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/05/09
FATTY LIVER-DISEASE
INDUCED CHOLESTASIS
STELLATE CELLS
PROBIOTICS
PROTECTS
INFLAMMATION
APOPTOSIS
OBESITY
AXIS
Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:
Dai,Manyun
;
Peng,Wan
;
Lin,Lisha
;
Wu,Zhanxuan
;
Zhang,Ting
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/07/17
Intestinal bleeding
Triptolide
Celastrol
Intestinal FXR
Tripterygium wilfordii
FARNESOID-X-RECEPTOR
BACTERIAL TRANSLOCATION
ACTIVATION
INFLAMMATION
DYSFUNCTION
TRIPTOLIDE
MICROBIOTA
PREVENTS
OBESITY
MICE
Inhibition of estrogen sulfation by Xian-Ling-Gu-Bao capsule
期刊论文
OAI收割
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2023, 卷号: 225, 页码: 12
作者:
He, Liangliang
;
Chen, Chanjuan
;
Duan, Shuyi
;
Li, Yang
;
Li, Chuan
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/11/11
Xian-Ling-Gu-Bao capsule
Estrogens
Sulfotransferase enzymes
Inhibitory effects
Molecular docking
Glycine-beta-muricholic acid antagonizes the intestinal farnesoid X receptor-ceramide axis and ameliorates NASH in mice
期刊论文
OAI收割
HEPATOLOGY COMMUNICATIONS, 2022, 页码: 16
作者:
Jiang, Jie
;
Ma, Yuandi
;
Liu, Yameng
;
Lu, Dasheng
;
Gao, Xiaoxia
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/11/11
Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal
期刊论文
OAI收割
CELL STEM CELL, 2022, 卷号: 29, 期号: 9, 页码: 1366-+
作者:
Chen, Li
;
Jiao, Tingying
;
Liu, Weiwei
;
Luo, Yuhong
;
Wang, Jue
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/04/10
Identification of naturally occurring inhibitors in Xian-Ling-Gu-Bao capsule against the glucuronidation of estrogens
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 17
作者:
He, Liangliang
;
Xu, Chunxia
;
Wang, Ziying
;
Duan, Shuyi
;
Xu, Jinjin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/04/10
Xian-Ling-Gu-Bao capsule
estrogens
glucuronidation
inhibitory effects
UDP-glucuronosyltransferase
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Zhong, Xian-Chun
;
Liu, Ya-Meng
;
Gao, Xiao-Xia
;
Krausz, Kristopher W.
;
Niu, Bing
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/08/16
nonalcoholic fatty liver disease
caffeic acid phenethyl ester
bile salt hydrolase
farnesoid X receptor
ceramide
gut microbiota
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
期刊论文
OAI收割
NATURE, 2022, 卷号: 604, 期号: 7906, 页码: 502-+
作者:
Trubetskoy, Vassily
;
Pardinas, Antonio F.
;
Qi, Ting
;
Panagiotaropoulou, Georgia
;
Awasthi, Swapnil
  |  
收藏
  |  
浏览/下载:113/0
  |  
提交时间:2022/05/16
Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
;
Feng, Chao
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics