中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
昆明植物研究所 [16]
上海药物研究所 [13]
大连化学物理研究所 [9]
广州生物医药与健康研... [8]
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期刊论文 [59]
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FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15
作者:
Wen, Ying-quan
;
Zou, Zi-yuan
;
Zhao, Guan-guan
;
Zhang, Meng-jiao
;
Zhang, Yong-xin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/22
MASLD/MASH
FXR
transcriptome
gut-liver axis
agonist
Inhibition of estrogen sulfation by Xian-Ling-Gu-Bao capsule
期刊论文
OAI收割
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2023, 卷号: 225, 页码: 12
作者:
He, Liangliang
;
Chen, Chanjuan
;
Duan, Shuyi
;
Li, Yang
;
Li, Chuan
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/11/11
Xian-Ling-Gu-Bao capsule
Estrogens
Sulfotransferase enzymes
Inhibitory effects
Molecular docking
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:
Zhao,Qi
;
Dai,Man-Yun
;
Huang,Ruo-Yue
;
Duan,Jing-Yi
;
Zhang,Ting
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/09
FATTY LIVER-DISEASE
INDUCED CHOLESTASIS
STELLATE CELLS
PROBIOTICS
PROTECTS
INFLAMMATION
APOPTOSIS
OBESITY
AXIS
Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:
Dai,Manyun
;
Peng,Wan
;
Lin,Lisha
;
Wu,Zhanxuan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/07/17
Intestinal bleeding
Triptolide
Celastrol
Intestinal FXR
Tripterygium wilfordii
FARNESOID-X-RECEPTOR
BACTERIAL TRANSLOCATION
ACTIVATION
INFLAMMATION
DYSFUNCTION
TRIPTOLIDE
MICROBIOTA
PREVENTS
OBESITY
MICE
Glycine-beta-muricholic acid antagonizes the intestinal farnesoid X receptor-ceramide axis and ameliorates NASH in mice
期刊论文
OAI收割
HEPATOLOGY COMMUNICATIONS, 2022, 页码: 16
作者:
Jiang, Jie
;
Ma, Yuandi
;
Liu, Yameng
;
Lu, Dasheng
;
Gao, Xiaoxia
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/11/11
Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal
期刊论文
OAI收割
CELL STEM CELL, 2022, 卷号: 29, 期号: 9, 页码: 1366-+
作者:
Chen, Li
;
Jiao, Tingying
;
Liu, Weiwei
;
Luo, Yuhong
;
Wang, Jue
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/04/10
Identification of naturally occurring inhibitors in Xian-Ling-Gu-Bao capsule against the glucuronidation of estrogens
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 17
作者:
He, Liangliang
;
Xu, Chunxia
;
Wang, Ziying
;
Duan, Shuyi
;
Xu, Jinjin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/04/10
Xian-Ling-Gu-Bao capsule
estrogens
glucuronidation
inhibitory effects
UDP-glucuronosyltransferase
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Zhong, Xian-Chun
;
Liu, Ya-Meng
;
Gao, Xiao-Xia
;
Krausz, Kristopher W.
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
nonalcoholic fatty liver disease
caffeic acid phenethyl ester
bile salt hydrolase
farnesoid X receptor
ceramide
gut microbiota
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
期刊论文
OAI收割
NATURE, 2022, 卷号: 604, 期号: 7906, 页码: 502-+
作者:
Trubetskoy, Vassily
;
Pardinas, Antonio F.
;
Qi, Ting
;
Panagiotaropoulou, Georgia
;
Awasthi, Swapnil
  |  
收藏
  |  
浏览/下载:105/0
  |  
提交时间:2022/05/16
Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics