中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
广州生物医药与健康研... [4]
大连化学物理研究所 [2]
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OAI收割 [15]
内容类型
期刊论文 [15]
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2022 [3]
2021 [3]
2020 [1]
2019 [1]
2014 [1]
2013 [1]
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学科主题
Pharmacolo... [4]
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Glycine-beta-muricholic acid antagonizes the intestinal farnesoid X receptor-ceramide axis and ameliorates NASH in mice
期刊论文
OAI收割
HEPATOLOGY COMMUNICATIONS, 2022, 页码: 16
作者:
Jiang, Jie
;
Ma, Yuandi
;
Liu, Yameng
;
Lu, Dasheng
;
Gao, Xiaoxia
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/11/11
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Zhong, Xian-Chun
;
Liu, Ya-Meng
;
Gao, Xiao-Xia
;
Krausz, Kristopher W.
;
Niu, Bing
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/08/16
nonalcoholic fatty liver disease
caffeic acid phenethyl ester
bile salt hydrolase
farnesoid X receptor
ceramide
gut microbiota
Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
;
Feng, Chao
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics
Myelocytomatosis-Protein Arginine N-Methyltransferase 5 Axis Defines the Tumorigenesis and Immune Response in Hepatocellular Carcinoma
期刊论文
OAI收割
HEPATOLOGY, 2021, 卷号: 74, 期号: 4, 页码: 1932-1951
作者:
Luo, Yuhong
;
Gao, Yuqing
;
Liu, Weiwei
;
Yang, Yuan
;
Jiang, Jie
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/21
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
OAI收割
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Intestinal MYC modulates obesity-related metabolic dysfunction
期刊论文
OAI收割
NATURE METABOLISM, 2021, 页码: 37
作者:
Luo, Yuhong
;
Yang, Shoumei
;
Wu, Xuan
;
Takahashi, Shogo
;
Sun, Lulu
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收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/08/17
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice
期刊论文
OAI收割
TOXICOLOGY LETTERS, 2020, 卷号: 333, 页码: 290-302
作者:
Zhao, Jie
;
Xie, Cen
;
Wang, Kanglong
;
Takahashi, Shogo
;
Krausz, Kristopher W.
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/21
Triptolide
Transcriptomics
Metabolomics
Apoptosis
Acylcarnitine
Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 期号: 10, 页码: 1396-1411
作者:
Xie, Cen
;
Takahashi, Shogo
;
Brocker, Chad N.
;
He, Shijun
;
Chen, Li
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Peroxisome proliferator-activated receptor alpha
Wy-14,643
Bile acid homeostasis
Farnesoid X receptor
Metabolomics
Metabolic profiling of praziquantel enantiomers
期刊论文
OAI收割
biochemical pharmacology, 2014, 卷号: 90, 期号: 2, 页码: 166-178
作者:
Wang, Haina
;
Fang, Zhong-Ze
;
Zheng, Yang
;
Zhou, Kun
;
Hu, Changyan
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2015/11/17
Cytochromes P450
Enantioselective metabolism
In silica metabolomics
Praziquantel
A model of in vitro UDP-glucuronosyltransferase inhibition by bile acids predicts possible metabolic disorders
期刊论文
OAI收割
journal of lipid research, 2013, 卷号: 54, 期号: 12, 页码: 3334-3344
作者:
Fang, Zhong-Ze
;
He, Rong-Rong
;
Cao, Yun-Feng
;
Tanaka, Naoki
;
Jiang, Changtao
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2015/11/09
cholestasis
endobiotics
structure-UDP-glucuronosyltransferase inhibition relationship
xenobiotics