中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共25条,第1-10条 帮助

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Unanticipated Quinoline Modification on Vancomycin as an Effective Strategy to Alter the Antibacterial Profile and Combat Multidrug Resistance 期刊论文  OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 46, 页码: 42670-42684
作者:  
Chang, Taopeng;  Chen, Zhifu;  Sheng, Lishu;  Bian, Xiaolei;  He, Peng
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A Broad-Spectrum Abietane Diterpenoid Derivative that Targets Lipid II Cycle and Bacterial Membrane to Combat Multidrug Resistance 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 19, 页码: 20487-20505
作者:  
Li, Yajing;  Yin, Ziqi;  Liu, Shuhui;  Bian, Xiaolei;  Chen, Zhifu
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Novel Rationally Designed Lipopeptides Derived from Bacitracin: Combating Multidrug Resistance and Evading Bacitracin Resistance via Potentiated Cell Wall and Membrane Inhibitions 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 15, 页码: 16410-16426
作者:  
Cheng, Sijie;  Liao, Jingwen;  Chen, Zhifu;  Li, Fang;  Zhu, Yanping
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Novel Aryl Sulfonium Modification on Vancomycin to Tackle MRSA and VRE In Vitro and In Vivo through Dual Enhanced Cell-Wall and Membrane Inhibition 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8310-8329
作者:  
Xie, Yuanyuan;  Wang, Xiaowen;  Chang, Taopeng;  Chen, Zhifu;  Luo, Youhong
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A Rationally Designed Sulfonium Lipoglycopeptide with Micelles Self-Assembly to Combat Multidrug Resistance via Dual Enhanced Cell Wall-Membrane Inhibition and T7SS Proteins Downregulation 期刊论文  OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 15, 页码: 12587-12603
作者:  
Xie, Yuanyuan;  Wang, Xiaowen;  Li, Fang;  Chen, Zhifu;  Li, Qun
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Single Amine or Guanidine Modification on Norvancomycin and Vancomycin to Overcome Multidrug-Resistance through Augmented Lipid II Binding and Increased Membrane Activity 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20639-20663
作者:  
Bian, Xiaolei;  Chen, Zhifu;  Li, Fang;  Xie, Yuanyuan;  Li, Yi
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Effect of initial pore water content and salinity on the resistivity of methane hydrate-bearing fine sediments 期刊论文  OAI收割
GAS SCIENCE AND ENGINEERING, 2024, 卷号: 124, 页码: 9
作者:  
Guan, Jinan;  Bo, Wenchao;  Wang, Shujia;  Liang, Yian;  Li, Dongliang
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A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3778-3794
作者:  
Guan, Dongliang;  Liu, Jiaxiang;  Chen, Feifei;  Li, Jian;  Wang, Xiaowen
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A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 14
作者:  
Guan, Dongliang;  Li, Jian;  Chen, Feifei;  Li, Jiaqi;  Bian, Xiaolei
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Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7179-7204
作者:  
Dong, Qian;  Tong, Mengya;  Yu, Xiaolu;  Wang, Lei;  Ao, Jiwei
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