中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [109]
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UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 237, 页码: 19
作者:
Wang, Li
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Bao, Xu-Bin
;
Tian, Chang-Qing
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/06/23
UBE4B
BET inhibitors
Resistance
KLHL22
JAK2
The combination of BET and METTL3 inhibitors elicits synergistic antitumor effects in ovarian cancer cells
via
reducing SP1 and BCL-2 expression
期刊论文
OAI收割
LIFE SCIENCES, 2025, 卷号: 368, 页码: 14
作者:
Ou, Ying-Jie
;
Liu, Ben-Jin
;
Xuan, Yi-Fei
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/24
BET inhibitor
METTL3 inhibitor
Combination therapy
SP1
BCL-2
Structure-Based Discovery of a Series of Novel MAT2a Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2025, 页码: 5
作者:
Zhou, Yushan
;
Wang, Li
;
Ren, Ruyue
;
Zhang, Junjie
;
Huan, Xiajuan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/05/27
MAT2a
MTAP
Synthetic lethality
Allosteric inhibitor
Structure-activity relationship
Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 653, 页码: 13
作者:
Sun, Ming-Dao
;
Lin, Qin
;
Ramezani, Jahandar
;
Liu, Jiang-Si
;
Lu, Zheng-An
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2025/04/03
Early Cretaceous
Aptian
CA-ID-TIMS geochronology
Astrochronology
Carbon isotope stratigraphy
Drought mediates
Sphagnum
defense response to herbivory
期刊论文
OAI收割
AMERICAN JOURNAL OF BOTANY, 2024, 卷号: N/A, 页码: 10
作者:
Chen, Yong-Da
;
Bu, Zhao-Jun
;
Wang, Meng
;
Zhang, Ming-Ming
;
Ma, Jin-Ze
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/12/30
combined stresses
growth-defense trade-off
peat moss
phenolics
soluble sugars
Sphagnaceae
climate warming
Chemoproteomics of Marine Natural Product Naamidine J Unveils CSE1L as a Therapeutic Target in Acute Lung Injury
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 14
作者:
Gao, Cheng-Long
;
Song, Jin-Qian
;
Yang, Ze-Nan
;
Wang, Haojie
;
Wu, Xin-Yuan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/11/05
Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:
Li, Hongrui
;
Liu, Ben-Jin
;
Xu, Jiahao
;
Song, Shan-Shan
;
Ba, Ruixian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/08/22
USP1 inhibitor
Structure -activity relationships
Olaparib-resistant cell
The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 716, 页码: 12
作者:
Xuan, Yi-Fei
;
Lu, Shan
;
Ou, Ying-Jie
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/07/12
MAT2A inhibitor
METTL3 inhibitor
m6A
Combination therapy
NSCLC
Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2024, 卷号: 223, 页码: 17
作者:
Zhang, Qian
;
Wu, Qian
;
Huan, Xia-Juan
;
Song, Shan -Shan
;
Bao, Xu-Bin
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/06/27
BET inhibitor
NAE inhibitor
BIM
Apoptosis
Combination therapy
Method for early diagnosis of verticillium wilt in cotton based on chlorophyll fluorescence and hyperspectral technology
期刊论文
OAI收割
COMPUTERS AND ELECTRONICS IN AGRICULTURE, 2024, 卷号: 216, 页码: 12
作者:
Yang, Mi
;
Kang, Xiaoyan
;
Qiu, Xiaofeng
;
Ma, Lulu
;
Ren, Hong
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2024/03/25
Wavelet transform
Features selection
Microstructure
Early detection of disease