机构

• 上海药物研究所 [31]
• 大连化学物理研究所 [3]
• 合肥物质科学研究院 [2]
• 过程工程研究所 [1]
• 上海生物化学与细胞生... [1]

采集方式

• OAI收割 [37]
• iSwitch采集 [1]

内容类型

• 期刊论文 [38]

发表日期

• 2024 [1]
• 2023 [3]
• 2022 [7]
• 2021 [4]
• 2020 [2]
• 2019 [5]
• 更多

学科主题

筛选

浏览/检索结果: 共38条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14 作者:  Chen, Xuetao;  Wu, Tingting;  Du, Zhiyan;  Kang, Wenjing;  Xu, Rujun   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/02/27 BET  BD1  Bromodomain  Brain-permeable  Multiple sclerosis   Discovery of 1H-Imidazo[4,5-b]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 13, 页码: 8725-8744 作者:  Chen, Xuetao;  Cao, Danyan;  Liu, Chihong;  Meng, Fanying;  Zhang, Zijian   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 17 作者:  Yan, Ziqin;  Lyu, Xilin;  Lin, Dongze;  Wu, Gaoxing;  Gong, Yang   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/10/17 Design, synthesis, and biological evaluation of BRD4 degraders 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 12 作者:  Ding, Mengyuan;  Shao, Yingying;  Sun, Danwen;  Meng, Suorina;  Zang, Yi   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10 PROTAC  BRD4 degradation  Leukemia  Multiple myeloma  Pulmonary fibrosis   Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non-Small Cell Lung Cancer Cells 期刊论文  OAI收割 MOLECULAR CANCER RESEARCH, 2022, 卷号: 20, 期号: 12, 页码: 1785-1798 作者:  Sun, Lin;  Wu, Qian;  Huan, Xia-Juan;  Tian, Chang-Qing;  Wang, Ying-Qing   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13 作者:  Luo, Menglan;  Wu, Qian;  Yang, Yueyue;  Sun, Lin;  Huan, Xiajuan   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/08/30 BET inhibitor  BRD4  Bivalent inhibitor  Anticancer   Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 14 作者:  Chen, Jingjing;  He, Huixin;  Wei, Aihuan;  Li, Yalei;  Cheng, Gang   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/08/16 PROTAC  Pyrrolopyridone  BRD4 S  Selectivity   BRD4 Targets the KEAP1-Nrf2-G6PD Axis and Suppresses Redox Metabolism in Small Cell Lung Cancer 期刊论文  OAI收割 ANTIOXIDANTS, 2022, 卷号: 11 作者:  Lv, Yang;  Lv, Xiaotong;  Zhang, Jiahui;  Cao, Guozhen;  Xu, Changzhi   |  收藏  |  浏览/下载：58/0  |  提交时间：2022/05/16 small cell lung cancer  BRD4  KEAP1  Nrf2  pentose phosphate pathway   Selective bromodomain and extra-terminal bromodomain inhibitor inactivates macrophages and hepatic stellate cells to inhibit liver inflammation and fibrosis 期刊论文  OAI收割 BIOENGINEERED, 2022, 卷号: 13, 期号: 4, 页码: 10914-10930 作者:  Fu, Rong;  Zu, Shi-Jia;  Liu, Yan-Jun;  Li, Jia-Cheng;  Dang, Wen-Zhen   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/06/15 BET inhibitor  macrophage  hepatic stellate cell  inflammation  fibrosis   Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma 期刊论文  OAI收割 CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218 作者:  Chen, Zi-qi;  Cao, Zhe-rui;  Wang, Yi;  Zhang, Xi;  Xu, Lan   |  收藏  |  浏览/下载：54/0  |  提交时间：2021/12/16 CYH33  MYC  P300  BET  B cell lymphoma  PI3K