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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [16]
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期刊论文 [35]
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Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5
作者:
Wang, Yujie
;
Xu, Keshi
;
Liu, Hongchun
;
Zhang, Wei
;
Hu, Chun
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/12/19
Auristatin E
beta-Glucuronidase
Antiproliferation
Tumor microenvironment
Variation of the coastal upwelling off South Java and their impact on local fishery resources
CNKI期刊论文
OAI收割
2023
作者:
Chunlong WEN
;
Zhenyan WANG
;
Jing WANG
;
Hongchun LI
;
Xingyu SHI
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/12/18
South Java
El Ni?o/La Ni?a-Southern Oscillation (ENSO)
Indian Ocean Dipole (IOD)
fishery resources
upwelling
Variation of the coastal upwelling off South Java and their impact on local fishery resources
期刊论文
OAI收割
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2023, 页码: 16
作者:
Wen, Chunlong
;
Wang, Zhenyan
;
Wang, Jing
;
Li, Hongchun
;
Shi, Xingyu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/12/07
South Java
El Nino
La Nina
Southern Oscillation (ENSO)
Indian Ocean Dipole (IOD)
fishery resources
upwelling
Comparison of short-offset and long-offset grounded-wire transient electromagnetic responses based on the 3D model
期刊论文
OAI收割
EXPLORATION GEOPHYSICS, 2023, 页码: 14
作者:
Chang, Jianghao
;
Xue, Junjie
;
Guo, Yongshuai
;
Yi, Hongchun
;
Li, Maofei
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/29
Transient electromagnetic method
grounded-wire
3D modelling
SOTEM
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:
Li, Daqiang
;
Zhang, Zhuo
;
Li, Yalei
;
Wang, Xinyi
;
Zhong, Hanyue
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 14
作者:
Chen, Jingjing
;
He, Huixin
;
Wei, Aihuan
;
Li, Yalei
;
Cheng, Gang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/08/16
PROTAC
Pyrrolopyridone
BRD4 S
Selectivity
Synthesis of the analogs of plocabulin and their preliminary structure-activity relationship study
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 51, 页码: 5
作者:
Wang, Leiming
;
Li, Xin
;
Cui, Hong
;
Lei, Xinsheng
;
Liu, Hongchun
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/12/01
Marine nature products
Plocabulin
PM060184
Synthesis
Antiproliferation
Effect of rubber substrates on the flexibility and tribological properties of diamond-like carbon coatings
期刊论文
OAI收割
Surface & Coatings Technology, 2021, 期号: 422, 页码: 127526
作者:
Yan Xu
;
Junhong Jia
;
Guangan Zhang
;
Hongchun Li
;
Tijun Chen
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/12/08
Diamond-like carbon film
Rubber elastomers
Adhesion
Tribological property
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Li, Yalei
;
Wang, Juan
;
Ding, Huaqian
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
Medulloblastoma
Hedgehog signaling
pathway
Drug resistance
GLI
BRD4
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:
Chen, Jingjing
;
Li, Yalei
;
Zhang, Jie
;
Zhang, Minmin
;
Wei, Aihuan
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/05/24
HDAC
BRD4
Selective dual inhibitors
Anticancer