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Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:
Zheng, Fuqiang
;
Hu, Zhengtao
;
Chen, Hai
;
Cheng, Jiaxin
;
Hou, Qiongqiong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
Heterocycle-fused phenylcyclohexylamines
Multi-target antagonists
NMDAR
Monoamine transporter
Antidepressants
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
The Overview and Trial Observations of AIMS
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Deng, Yuanyong
;
Wang, Dongguang
;
Hua, Jianwen
;
Xu, Songbo
;
Liang, Ming
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/07/14
Sun: infrared
methods: observational
instrumentation: spectrographs
A pulsar-helium star compact binary system formed by common envelope evolution
期刊论文
OAI收割
SCIENCE, 2025, 卷号: 388, 期号: 6749, 页码: 859-863
作者:
Yang, Z. L.
;
Han, J. L.(1,2*)
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/06/04
De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
;
Shan, Yiming
;
Huang, Lujia
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Screening and preparation of nanobodies for SIGLEC-15 detection
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2025, 卷号: 229, 页码: 9
作者:
Zhao, Shuaiying
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2025/04/01
SIGLEC-15
Nanobody
Expression
Purification
Divergent Synthesis of Dihydrofuran and Dienol Scaffolds via Pd-Catalyzed Decarboxylative Carbene Cross-Coupling
期刊论文
OAI收割
ORGANIC LETTERS, 2025, 卷号: 27, 期号: 18, 页码: 4753-4761
作者:
Ma, Xiaolong
;
Miao, Erfei
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
Synergistic Zn-Cd Bimetallic Engineering in ZIFs for High-Chloride 2e
-
ORR to H
2
O
2
in Simulated Neutral Seawater
期刊论文
OAI收割
MATERIALS, 2025, 卷号: 18, 期号: 8, 页码: 10
作者:
Wang, Xu
;
Wang, Nan
;
Liu, Kunpeng
;
Yang, Meinan
;
Zhang, Ruiyong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/07/11
oxygen reduction reaction
neutral condition
electrocatalysis
H2O2
seawater
Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2025/04/01
LC3B
CDK9
Degradation
Protein complex
Bicyclic polyprenylated acylphloroglucinol-related meroterpenoids as potent DRAK2 inhibitors from
Hypericum patulum
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 232, 页码: 10
作者:
Huang, Jin-Chang
;
Jia, Xin-Yu
;
Lv, Yi-Fan
;
Xu, Hong-Hong
;
Han, Ming
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
Hypericum patulum
Hypericaceae
Meroterpenoids
Hyperpatins A-H
Death-associated protein kinase-related
apoptosis-inducing kinase 2
Glucose-stimulated insulin secretion