中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
半导体研究所 [7]
广州地球化学研究所 [5]
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期刊论文 [53]
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2026 [1]
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光电子学 [5]
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From Hit to Lead: Discovery of Novel Selective RIPK1 Inhibitor with Pyridoimidazole Scaffold for the Treatment of Autoimmune Diseases through Phenotypic Screening and Structural Optimization
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 69, 期号: 3, 页码: 3252-3288
作者:
Wan, Jihong
;
Xiong, Xiao-Yu
;
Geng, Zixiang
;
Yuan, Benjun
;
Ma, Youzhen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2026/04/01
Global Energy Transition and Low Carbon Technology Pathways
期刊论文
OAI收割
ENERGIES, 2025, 卷号: 18, 期号: 21, 页码: 5701
作者:
Shen, Lei
;
Elshkaki, Ayman
;
Zhong, Shuai
;
Hu, Xueyue
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/12/19
Progress and Policy Considerations to Achieve Energy Transition and Carbon Mitigation
期刊论文
OAI收割
ENERGIES, 2025, 卷号: 18, 期号: 21, 页码: 5680
作者:
Shen, Lei
;
Elshkaki, Ayman
;
Li, Delong
;
Zhong, Shuai
;
Wu, Xinyi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/12/19
A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in
KRAS
-driven cancers
期刊论文
OAI收割
CANCER CELL, 2025, 卷号: 43, 期号: 10, 页码: 32
作者:
Feng, Juanjuan
;
Xiao, Xuanzheng
;
Xia, Xinting
;
Min, Jian
;
Tang, Weiying
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/12/04
Identification and mechanism of hepatoprotective saponins and metabolites in the sweet variant of
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 165, 页码: 13
作者:
Wang, Hanghang
;
Chen, Chen
;
Xue, Mingzhen
;
Zhang, Yu
;
Chen, Keming
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/12/04
Gynostemma pentaphyllum
Gypenoside
Gut metabolite
Liver protection
Hepatic stellate cells
Multiomics Reveals the Mechanism of
Natranaerobius thermophilus
Adaptation to Combined Hypersaline, Alkaline, and Elevated Temperature Environments
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2025, 卷号: 24, 期号: 8, 页码: 4243-4258
作者:
Xing, Qinghua
;
Tao, Xinyi
;
Zhang, Shanshan
;
Mesbah, Noha M.
;
Mao, Xinwei
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/12/03
polyextremophile
three-extremes
multiomics
hypersaline
alkaline
elevatedtemperature
Natranaerobius thermophilus
Development of 3-arylaminothiophenic-2-carboxylic acid derivatives as new FTO inhibitors showing potent antileukemia activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 17
作者:
Zhang, Deyan
;
Liu, Lu
;
Li, Ming
;
Hu, Xinyi
;
Zhang, Xi
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2025/04/24
RNA modification
N 6-methyladenosine
Demethylase FTO
Structure-activity relationship
Antileukemia
Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel
Hs
ClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:
Sun, Mingyang
;
Chen, Beijing
;
Teng, Dan
;
Zhao, Hongshen
;
Liao, Yilie
  |  
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2025/04/01
Density functional theory calculation for understanding the roles of biochar in immobilizing exchangeable Al3+and enhancing soil quality in acidic soils
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2025, 卷号: 290, 页码: 12
作者:
He, Debo
;
Liu, Xinyi
;
Hu, Dongni
;
Lei, Ping
;
Zhang, Jinbo
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2025/03/24
Soil amendments
Soil acidification
Soil nitrogen transformation
15N double labelling
Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Chen, Beijing
;
Sun, Mingyang
;
Zhang, Chun
;
Huang, Qi
;
Teng, Dan
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2024/12/25