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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
化学研究所 [2]
武汉植物园 [2]
近代物理研究所 [2]
地理科学与资源研究所 [1]
大连化学物理研究所 [1]
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OAI收割 [26]
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期刊论文 [28]
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2024 [4]
2023 [1]
2019 [1]
2018 [3]
2017 [3]
2016 [5]
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Science & ... [1]
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PROTAC derivatization of natural products for target identification and drug discovery: Design of evodiamine-based PROTACs as novel REXO4 degraders
期刊论文
OAI收割
JOURNAL OF ADVANCED RESEARCH, 2024, 卷号: 63, 页码: 219-230
作者:
Chen, Shuqiang
;
Bi, Kaijian
;
Liang, Huixin
;
Wu, Zhe
;
Huang, Min
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/10/21
PROTAC
Natural products
Target identification
Quantitative proteomics
Antitumor activities
Responses of Intraspecific and Interspecific Trait Variations to Nitrogen Addition in a Tibetan Alpine Meadow
期刊论文
OAI收割
PLANTS-BASEL, 2024, 卷号: 13, 期号: 13, 页码: 1764
作者:
Yu, Jialuo
;
Shi, Peili
;
Zong, Ning
;
Song, Minghua
;
Miao, Yujue
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/08/22
community weighted mean
community non-weighted mean
interspecific and intraspecific variation
nitrogen addition
alpine meadows
Site- and Stereoselective Glycomodification of Biomolecules through Carbohydrate-Promoted Pictet-Spengler Reaction
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 页码: 11
作者:
Liu, Bo
;
Zou, Xiangman
;
Zhang, Yue
;
Yang, Yang
;
Xu, Hao
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/05/07
The predictive role of early inflammation and oxidative stress and the dynamics of cytokines networks in post-stroke depression
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2024, 卷号: 347, 页码: 469-476
作者:
Wen, Lulu
;
Yan, Chuming
;
Si, Tong
;
Huang, Liyuan
;
Nie, Yuting
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/01/22
Post stroke depression
Cytokines
Oxidative stress
Biomarker
Inflammation
A de novo evolved gene contributes to rice grain shape difference between indica and japonica
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 5906
作者:
Chen,Rujia
;
Xiao,Ning
;
Lu,Yue
;
Tao,Tianyun
;
Huang,Qianfeng
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/05/09
NATURAL VARIATION
ORIGIN
SIZE
PROTEIN
GENOME
ASSOCIATION
PREDICTION
DIVERSITY
SEQUENCE
QUALITY
Metabolome and transcriptome analyses reveal quality change in the orange-rooted Salvia miltiorrhiza (Danshen) from cultivated field
期刊论文
OAI收割
Chinese Medicine, 2019, 卷号: 14, 期号: 1
作者:
Zhan,Zhilai
;
Fang,Wentao
;
Ma,Xiaohui
;
Chen,Tong
;
Cui,Guanghong
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/10/17
Salvia miltiorrhiza Bunge (Danshen)
Tanshinones
Metabolome profiling
mRNA expression profiling
ER-associated degradation
Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3808-3812
作者:
Zheng, Qiangang
;
Chen, Ziqi
;
Wan, Huixin
;
Tang, Shuai
;
Ye, Yan
  |  
收藏
  |  
浏览/下载:247/0
  |  
提交时间:2019/01/08
IDH1 inhibitor
Imidazole cyclopropyl amine
Structure-based rational design
Genomic Analyses from Non-invasive Prenatal Testing Reveal Genetic Associations, Patterns of Viral Infections, and Chinese Population History
期刊论文
OAI收割
CELL, 2018, 卷号: 175, 期号: 2, 页码: 347-+
作者:
Liu, Siyang
;
Huang, Shujia
;
Chen, Fang
;
Zhao, Lijian
;
Yuan, Yuying
  |  
收藏
  |  
浏览/下载:95/0
  |  
提交时间:2019/04/28
Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 140-153
作者:
Zha, Chuantao
;
Deng, Wenjia
;
Fu, Yan
;
Tang, Shuai
;
Lan, Xiaojing
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2019/01/08
Structure-based drug design
Selective CDK4/6 inhibitors
Structure-activity relationship study
In vivo antitumor activity
Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5262-5266
作者:
Zheng, Qiangang
;
Tang, Shuai
;
Fu, Xianlei
;
Chen, Ziqi
;
Ye, Yan
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
IDH1 inhibitor
Indane amide
Structure-based rational design