中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共44条,第1-10条 帮助

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Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel HsClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:  
Sun, Mingyang;  Chen, Beijing;  Teng, Dan;  Zhao, Hongshen;  Liao, Yilie
  |  收藏  |  浏览/下载:10/0  |  提交时间:2025/04/01
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:  
Chen, Jiexuan;  Wu, Mingfei;  Mo, Jun;  Hong, Ju;  Wang, Wei
  |  收藏  |  浏览/下载:13/0  |  提交时间:2025/04/01
Discovery of N-Benzylpiperidinol derivatives as USP7 inhibitors against Hematology 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 13
作者:  
Pan, Youlu;  Chen, Haifeng;  Fu, Jingfeng;  Zhang, Jingyu;  Wang, Peipei
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/10/21
Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:  
Chen, Beijing;  Sun, Mingyang;  Zhang, Chun;  Huang, Qi;  Teng, Dan
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/12/25
Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759
作者:  
Liu, Zhi;  Jiang, Kailong;  Liu, Yan;  Li, Junfei;  Huang, Siqi
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/09/26
Design, Synthesis, and Biological Evaluation of 2,4-Diaminopyrimidine Derivatives as Potent CDK7 Inhibitors 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 8
作者:  
Zhang, Hualin;  Tu, Yutong;  Tao, Zhaofan;  Gao, Lixin;  Huang, Shengjie
  |  收藏  |  浏览/下载:9/0  |  提交时间:2024/08/22
Discovery of Orally Bioavailable and Potent CDK9 Inhibitors for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 12, 页码: 10035-10056
作者:  
Wang, Wen-Jing;  Gao, Lixin;  Wang, Simei;  Huang, Wensi;  Meng, Xin-Yu
  |  收藏  |  浏览/下载:5/0  |  提交时间:2024/08/20
Moisture source differences between the 2020 and 1998 super Meiyu-flood events in the Yangtze River Valley 期刊论文  OAI收割
WEATHER AND CLIMATE EXTREMES, 2024, 卷号: 43, 页码: 100644
作者:  
Zhang, Chi;  Tang, Qiuhong;  Zhao, Yang;  Chen, Deliang;  Huang, Jinchuan
  |  收藏  |  浏览/下载:40/0  |  提交时间:2024/04/08
Quantifying precipitation moisture contributed by different atmospheric circulations across the Tibetan Plateau 期刊论文  OAI收割
JOURNAL OF HYDROLOGY, 2024, 卷号: 628, 页码: 130517
作者:  
Zhang, Chi;  Zhang, Xu;  Tang, Qiuhong;  Chen, Deliang;  Huang, Jinchuan
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/01/04
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:  
Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng
  |  收藏  |  浏览/下载:131/0  |  提交时间:2023/12/19