机构

• 上海药物研究所 [9]
• 近代物理研究所 [1]

采集方式

• OAI收割 [10]

内容类型

• 期刊论文 [10]

发表日期

• 2025 [2]
• 2024 [1]
• 2023 [2]
• 2022 [1]
• 2021 [1]
• 2019 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共10条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of 2-tetrahydroisoquinoline substituted quinazoline derivatives as lysine methyltransferase G9a inhibitors with in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 300, 页码: 15 作者:  Shao, Mengjie;  Gao, Lixin;  Xu, Jiahui;  Zhu, Lingfeng;  Lu, Yiting   |  收藏  |   A patent review of CHK1 inhibitors (2019-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2025, 卷号: 35, 期号: 9, 页码: 915-931 作者:  Liu, Tao;  Su, Mingbo;  Wang, Yuxuan;  Gao, Anhui;  Jiang, Kailong   |  收藏  |   Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759 作者:  Liu, Zhi;  Jiang, Kailong;  Liu, Yan;  Li, Junfei;  Huang, Siqi   |  收藏  |   Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |   Discovery of toxoflavin,a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 234 作者:  Liu Changmei;  Nie Litong;  Jiang Haini;  Xu Lei;  Zhang Kunzhi   |  收藏  |   Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia 期刊论文  OAI收割 LEUKEMIA, 2022, 页码: 11 作者:  Jiang, Kailong;  Li, Xuemei;  Wang, Chang;  Hu, Xiaobei;  Wang, Peipei   |  收藏  |   Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia 期刊论文  OAI收割 CHEMMEDCHEM, 2021, 页码: 12 作者:  Jin, Tingting;  Wang, Peipei;  Long, Xiubing;  Jiang, Kailong;  Song, Pinrao   |  收藏  |   Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62 作者:  Tong, Lexian;  Song, Pinrao;  Jiang, Kailong;  Xu, Lei;  Jin, Tingting   |  收藏  |   Alpha Decay of the Neutron-deficient Isotopes 215,216U 期刊论文  OAI收割 原子核物理评论, 2016, 页码: 217-220 作者:  Zhang Zhiyuan;  Gan Zaiguo;  Ma Long;  Yang Huabin;  Wang Jianguo   |  收藏  |   Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cell growth 期刊论文  OAI收割 CANCER LETTERS, 2015, 卷号: 360, 期号: 2, 页码: 257-268 作者:  Huang, Hejing;  Liu, Huanan;  Liu, Changmei;  Fan, Lixia;  Zhang, Xinwen   |  收藏  |