机构

• 上海药物研究所 [10]
• 海洋研究所 [2]

采集方式

• OAI收割 [12]

内容类型

• 期刊论文 [12]

发表日期

• 2023 [1]
• 2022 [3]
• 2021 [1]
• 2020 [3]
• 2019 [1]
• 2018 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共12条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14 作者:  Guo, Siqi;  Jia, Tongguan;  Xu, Xiaoming;  Yang, Feng;  Xiao, Senhao   |  收藏  |  浏览/下载：33/0  |  提交时间：2023/04/10 ENL Inhibitor  YEATS domain  Histone lysine acetylation  Benzimidazole derivatives  Acute myeloid leukemia   A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1 beta and IL-6 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4180-4192 作者:  Liao, Liping;  Dang, Wenzhen;  Lin, Tingting;  Yu, Jinghua;  Liu, Tonghai   |  收藏  |  浏览/下载：31/0  |  提交时间：2023/04/10 Glycolysis  Phosphoglycerate kinase 1  Macrophages  NRF2  Inflammation   High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 2, 页码: 14 作者:  Xiao, Senhao;  Guo, Siqi;  Han, Jie;  Sun, Yanli;  Wang, Mingchen   |  收藏  |  浏览/下载：45/0  |  提交时间：2022/06/15 Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 2, 页码: 470 作者:  Li Wen;  Liao Liping;  Song Ning;  Liu Yanjun;  Ding Yiluan   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/05/22 glyceraldehyde 3-phosphate dehydrogenase  1  2  3  4  6-penta-O-galloyl-β-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Discovery of High-Affinity Inhibitors of the BPTF Bromodomain 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12075-12088 作者:  Lu, Tian;  Lu, Haibo;  Duan, Zhe;  Wang, Jun;  Han, Jie   |  收藏  |  浏览/下载：55/0  |  提交时间：2021/11/04 Chromosome-level genome assembly of Paralithodes platypus provides insights into evolution and adaptation of king crabs 期刊论文  OAI收割 MOLECULAR ECOLOGY RESOURCES, 2020, 页码: 15 作者:  Tang, Boping;  Wang, Zhongkai;  Liu, Qiuning;  Wang, Zhengfei;  Ren, Yandong   |  收藏  |  浏览/下载：88/0  |  提交时间：2021/04/12 adaptation  blue king crab  evolution  genome   Discovery of 8-Methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one Derivatives as Highly Potent and Selective Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 3956-3975 作者:  Li, Zizhou;  Xiao, Senhao;  Yang, Yaxi;  Chen, Chao;  Lu, Tian   |  收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01 High-Quality Genome Assembly of Eriocheir japonica sinensis Reveals Its Unique Genome Evolution 期刊论文  OAI收割 FRONTIERS IN GENETICS, 2020, 卷号: 10, 页码: 9 作者:  Tang, Boping;  Wang, Zhongkai;  Liu, Qiuning;  Zhang, Huabin;  Jiang, Senhao   |  收藏  |  浏览/下载：47/0  |  提交时间：2020/09/21 Eriocheir japonica sinensis  evolution  nanopore  crab  genome assembly and annotation   Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500 作者:  Zhang, Dan;  Han, Jie;  Lu, Wenchao;  Lian, Fulin;  Wang, Jun   |  收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01 Lysine acetylation  Bromodomain  Virtual screening  BPTF inhibitor   Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20, 页码: 5397-5407 作者:  Lu, Wenchao;  Xiong, Huan;  Chen, Yu;  Wang, Chen;  Zhang, Hao   |  收藏  |  浏览/下载：145/0  |  提交时间：2019/01/08 Drug discovery  Epigenetics  Histone acetyltransferase  P300/CBP