中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共16条,第1-10条 帮助

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Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 15
作者:  
Tang, Siyuan;  Hu, Shuyang;  Feng, Lijing;  Kong, Linghui;  Gui, Jiangwen
  |  收藏  |  浏览/下载:1/0  |  提交时间:2025/05/27
Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 9, 页码: 7112-7129
作者:  
Li, Zixiang;  Ye, Rufeng;  He, Qian;  Lu, Jiashuo;  Sun, Yanting
  |  收藏  |  浏览/下载:27/0  |  提交时间:2024/06/27
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:  
Kong, Linghui;  Ning, Kuan;  Liu, Xiao;  Lu, Jiashuo;  Chen, Baiyu
  |  收藏  |  浏览/下载:39/0  |  提交时间:2023/10/17
SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:  
Kong, Linghui;  Shu, Xuelian
  |  收藏  |  浏览/下载:62/0  |  提交时间:2022/08/30
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:  
He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui
  |  收藏  |  浏览/下载:91/0  |  提交时间:2021/11/04
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文  OAI收割
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:  
Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li
  |  收藏  |  浏览/下载:100/0  |  提交时间:2021/05/24
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  
Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
  |  收藏  |  浏览/下载:91/0  |  提交时间:2020/07/01
Spatial Distribution of Macroinvertebrate Community along a Longitudinal Gradient in a Eutrophic Reservoir-Bay during Different Impoundment Stages, China 期刊论文  OAI收割
INTERNATIONAL REVIEW OF HYDROBIOLOGY, 2012, 卷号: 97, 期号: 3, 页码: 169-183
作者:  
Zhang, Min;  Cai, Qinghua;  Xu, Yaoyang;  Kong, Linghui;  Tan, Lu
  |  收藏  |  浏览/下载:30/0  |  提交时间:2012/09/25
ZONATION AND ITS INFLUENCING FACTORS OF A LARGE SUBTROPICAL RESERVOIR (DANJIANGKOU RESERVOIR IN CENTRAL CHINA), BASED ON MACROINVERTEBRATES 期刊论文  OAI收割
FRESENIUS ENVIRONMENTAL BULLETIN, 2012, 卷号: 21, 期号: 8, 页码: 2095-2104
作者:  
Zhang, Min;  Cai, Qinghua;  Xu, Yaoyang;  Wang, Lan;  Kong, Linghui
收藏  |  浏览/下载:30/0  |  提交时间:2013/01/09
Longitudinal patterns of phytoplankton distribution in a tributary bay under reservoir operation 期刊论文  OAI收割
QUATERNARY INTERNATIONAL, 2011, 卷号: 244, 期号: 2, 页码: 280-288
作者:  
Wang, Lan;  Cai, Qinghua;  Zhang, Min;  Tan, Lu;  Kong, Linghui
  |  收藏  |  浏览/下载:31/0  |  提交时间:2011/12/22