中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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西北高原生物研究所 [75]
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期刊论文 [587]
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Molecular recognition of two approved drugs Macimorelin and Anamorelin by the growth hormone secretagogue receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 11
作者:
Wang, Ruo-lan
;
Sun, Jun
;
Liu, Heng
;
Guo, Shi-meng
;
Zhang, Yu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
growth hormone secretagogue receptor
anamorelin
macimorelin
molecular recognition
Substrate recognition and cleavage mechanism of the monkeypox virus core protease
期刊论文
OAI收割
NATURE, 2025, 页码: 29
作者:
Gao, Yan
;
Xie, Xiong
;
Zhang, Xiaoyu
;
Cao, Junyuan
;
Lan, Weiqi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
In vitro
and
In vivo
Drug Metabolism Analysis of BPI-460372-A Covalent TEAD1/3/4 Inhibitor
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2025, 页码: 15
作者:
Liu, Xiaoyun
;
Zhong, Dafang
;
Tang, Chongzhuang
;
Xu, Xiaofeng
;
Lan, Hong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/24
Hippo signaling pathway
TEAD inhibitor
covalent inhibitor
BPI-460372
UHPLC-Orbitrap-HRMS
cysteine
S
-conjugate
beta
-lyase.
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
Large-sample detection of reservoir impacts on flow regime alteration through improved paired-catchment approach
期刊论文
OAI收割
JOURNAL OF HYDROLOGY, 2024, 卷号: 642, 页码: 131872
作者:
Bai, Xinli
;
Liu, Wenbin
;
Wang, Tingting
;
Feng, Yao
;
Wang, Hong
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/10/21
Paired-catchment approach
Large-sample comparison
Reservoir impact
Flow regime alteration
Preliminary compact torus injection experiments on the Keda Torus eXperiment reversed field pinch
期刊论文
OAI收割
PLASMA SCIENCE & TECHNOLOGY, 2024, 卷号: 26
作者:
Lan, Tao
;
Chen, Chen
;
Xiao, Chijin
;
Ding, Weixing
;
Wu, Jie
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/11/20
compact torus
fueling
reversed field pinch
density limit
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2024/09/10
Target Identification and Mechanistic Characterization of Indole Terpenoid Mimics: Proper Spindle Microtubule Assembly Is Essential for Cdh1-Mediated Proteolysis of CENP-A
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 14
作者:
Peng, Yan
;
Zhang, Yumeng
;
Fang, Ruan
;
Jiang, Hao
;
Lan, Gongcai
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2024/07/12
Cdh1
CENP-A regulation
colchicine-binding site inhibitor
indole terpenoid
target identification
Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 12, 页码: 1963-1977
作者:
Gai, Xiameng
;
Liu, Yingluo
;
Lan, Xiaojing
;
Chen, Luoyi
;
Yuan, Tao
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/08/20
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:
Xie, Xiong
;
Lan, Qiaoshuai
;
Zhao, Jinyi
;
Zhang, Sulin
;
Liu, Lu
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/05/07