中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2022 [1]
2021 [1]
2020 [2]
2019 [1]
2018 [2]
学科主题
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Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 1, 页码: 228-245
作者:
Li, Heng
;
Zhang, Yao
;
Liu, Moting
;
Fan, Chen
;
Feng, Chunlan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/06/15
Ulcerative colitis
Mucosal homeostasis
Gut microbiota
Epithelial barrier
PDE4
Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Lu, Qiu-kai
;
Fan, Chen
;
Xiang, Cai-gui
;
Wu, Bing
;
Lu, Hui-min
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/06/11
PDE4
apremilast
skin fibrosis
macrophages
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:
Li, Heng
;
Li, Jian
;
Zhang, Xianglei
;
Feng, Chunlan
;
Fan, Chen
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
DC591017
PDE4
Inflammation
Macrophages
Dendritic cells
Psoriasis
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:
Li, Heng
;
Li, Jian
;
Zhang, Xianglei
;
Feng, Chunlan
;
Fan, Chen
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
DC591017
PDE4
Inflammation
Macrophages
Dendritic cells
Psoriasis
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2209-2226
作者:
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Solid-state characterization and solubility enhancement of apremilast drug-drug cocrystals
期刊论文
OAI收割
CRYSTENGCOMM, 2018, 卷号: 20, 期号: 39, 页码: 5945-5948
作者:
Wang, Feng-Yuan
;
Zhang, Qi
;
Zhang, Zaiyong
;
Gong, Xiaoyi
;
Wang, Jian-Rong
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2019/01/08
Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Li, Heng
;
Zuo, Jianping
;
Tang, Wei
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
phosphodiesterase-4
psoriasis
atopic dermatitis
inflammatory airway diseases
inflammatory bowel
disease
roflumilast
apremilast
crisaborole