中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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高能物理研究所 [163]
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Design, synthesis, and activity evaluation of indole derivatives as potential stabilizers for p53 Y220C
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 121, 页码: 9
作者:
Li, Linquan
;
Gu, Xi
;
Meng, Jingyi
;
Wen, Yiming
;
Yi, Jing
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/05/27
p53 Y220C
Synthesis
Structural modification
Drug design
Discovery and Extensive Follow-up of SN 2024ggi, a Nearby Type IIP Supernova in NGC 3621
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 983, 期号: 1
作者:
Chen, Ting-Wan
;
Yang, Sheng
;
Srivastav, Shubham
;
Moriya, Takashi J.
;
Smartt, Stephen J.
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2025/04/21
Glabridin as a selective Kv2.1 inhibitor ameliorates DPN pathology by disrupting the Aβ/Kv2.1/JNK/NF-κB/NLRP3/p-Tau pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 17
作者:
Xu, Jia-wen
;
Ma, Lin
;
Xiang, Yu
;
Dai, Meng-qing
;
Li, Qiu-hui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/27
diabetic peripheral neuropathy
glabridin
Kv2.1
dorsal root ganglia
Schwann cells
A beta/Kv2.1/NLRP3/p-Tau axis
Enhanced early strength and microstructural stability of dredged sludge using CPCS curing agent
期刊论文
OAI收割
CONSTRUCTION AND BUILDING MATERIALS, 2025, 卷号: 466, 页码: 16
作者:
Dong, Meng
;
Wen, Xiaodong
;
Lang, Lei
;
Jin, Jiaxu
;
Li, Jiang-Shan
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/06/27
Dredged sludge
Curing agent
Mechanical properties
Microscopic properties
Solidification mechanism
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Molecular basis of lipid and ligand regulation of prostaglandin receptor DP2
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 51, 页码: 12
作者:
Xu, Jiuyin
;
Xu, Youwei
;
Hou, Li
;
He, Xinheng
;
Li, Yang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/02/28
prostaglandin receptor
DP2
lipid regulation
receptor activation
signal bias
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/04/01
Integration of ion mobility-quadrupole time-of-flight mass spectrometry and triple quadrupole-ion trap mass spectrometry coupled with ultra-high performance liquid chromatography for characterizing and quantitatively assay the saponins of
Panax
quinquefolius
flower
期刊论文
OAI收割
MICROCHEMICAL JOURNAL, 2024, 卷号: 207, 页码: 14
作者:
Wang, Yu
;
Hong, Li-li
;
Sun, Meng-xiao
;
Li, Xue
;
Zou, Ya-dan
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/12/16
Panax quinquefolius flower
UHPLC/IM-QTOF-MS
UHPLC/QTrap-MS
Multi-component characterization
Quantitative assay
Accurately Estimating Redshifts from CSST Slitless Spectroscopic Survey Using Deep Learning
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2024, 卷号: 977, 期号: 1
作者:
Zhou, Xingchen
;
Gong, Yan
;
Zhang, Xin
;
Li, Nan
;
Meng, Xian-Min
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/12/16
The JCMT BISTRO Survey: The Magnetic Fields of the IC 348 Star-forming Region
期刊论文
OAI收割
The Astrophysical Journal, 2024, 卷号: 977, 期号: 1, 页码: 32
作者:
Choi,Youngwoo
;
Kwon,Woojin
;
Pattle,Kate
;
Arzoumanian,Doris
;
Bourke,Tyler L.
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/01/02