中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Electron acceptor motif-manipulated NIR-II AIE photosensitizers synergically induce tumor pyroptosis through multimodal image-guided pure type I photodynamic and photothermal therapy
期刊论文
OAI收割
BIOMATERIALS, 2026, 卷号: 324, 页码: 14
作者:
Xiang, Chunbai
;
Liu, Yu
;
Ding, Qihang
;
Jiang, Ting
;
Li, Chao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Type-I photosensitizers
Pyroptosis
Aggregation-induced emission
Immunotherapy
Kadcoccinoids A-K, triterpenoids from
Kadsura coccinea
with PCSK9 expression inhibitory activities
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 238, 页码: 13
作者:
Duan, Yelin
;
Chen, Tong
;
Guo, Pengju
;
Li, Chenyue
;
Chen, Yihan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/08/20
Kadsura coccinea
Schisandraceae
Lanostane-type triterpenoids
Protostane-type triterpenoids
PCSK9
Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10
作者:
Zhang, Chun
;
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Cao, Qing
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Imidazo[2,1-b][1,3,4]thiadiazole
Inhibitory activities
Fluorescence imaging
Zebrafish
SHP2
Phytochemical and biological studies on rare and endangered plants endemic to China. Part XLIV. Integrated NMR/EI-MS/LC-PDA-ESIMS approach for dereplication and targeted isolation of fortunefuroic acids from
Keteleeria
fortunei
across diverse geographical origins
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 235, 页码: 13
作者:
Zhao, Ze-Yu
;
Jiang, Zhe-Lu
;
Tong, Ying-Peng
;
Chi, Chun-Jing
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/04/24
Keteleeria fortunei
Pinaceae
Geographical origins
Integrated NMR/EI-MS/LC-PDA-ESIMS
methods
Fortunefuroic acids
ATP-Citrate lyase
The Overview and Trial Observations of AIMS
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Deng, Yuanyong
;
Wang, Dongguang
;
Hua, Jianwen
;
Xu, Songbo
;
Liang, Ming
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/07/14
Sun: infrared
methods: observational
instrumentation: spectrographs
Advancing active compound discovery for novel drug targets: insights from AI-driven approaches
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12
作者:
Wang, Xing-you
;
Chen, Yang
;
Li, Yu-fan
;
Wei, Chao-yang
;
Liu, Meng-ya
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
AI-driven drug discovery
novel drug targets
molecular design
ligand exploration
phenotypic drug discovery
undruggable targets
Comparative transcriptomic analysis reveals a differential acid response mechanism between estuarine oyster (Crassostrea ariakensis) and Pacific oyster (Crassostrea gigas)
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2025, 卷号: 297, 页码: 12
作者:
Wang, Shen-Tong
;
Yang, Qi
;
Liu, Ming-Kun
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/07/11
Front-loading
Ion channel
Ocean and coastal acidification
Oyster
Resilience
Translational control
Characterization of the Biological Effect Mediated by Mycobacterial Kinase PknG on Protein Phosphorylation and Acetylation
期刊论文
OAI收割
ACS OMEGA, 2025, 卷号: 10, 期号: 21, 页码: 21662-21673
作者:
Xie, Shuyu
;
Liu, Tianqi
;
Zhang, Luoxi
;
Yang, Yang
;
Tang, Yanqing
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/07/25
PRL-3: unveiling a new horizon in cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 11
作者:
Cao, Zi-tong
;
Mao, Jia-luo
;
Huang, Chang-ying
;
Wang, Han-lin
;
Wang, Ming-zhi
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/06/23
Phosphatase of Regenerating Liver-3 (PRL3)
tumor metastasis
targeted therapies
PRL-3-zumab
A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 298, 页码: 13
作者:
Tong, Yongliang
;
Chen, Runqiu
;
Lu, Xinrong
;
Chen, Cuiying
;
Sun, Guiqin
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/04/01
Glycol-immunology
Nanobody-enzyme fusion protein
Sialic acid