中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [15]
烟台海岸带研究所 [2]
金属研究所 [1]
过程工程研究所 [1]
上海光学精密机械研究... [1]
采集方式
OAI收割 [20]
内容类型
期刊论文 [20]
发表日期
2024 [3]
2023 [4]
2022 [2]
2021 [2]
2019 [2]
2018 [1]
更多
学科主题
Environmen... [1]
Environmen... [1]
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Optimization and Biological Evaluation of Novel 1
H
-Pyrrolo[2,3-
c
]pyridin Derivatives as Potent and Reversible Lysine Specific Demethylase 1 Inhibitors for the Treatment of Acute Myelogenous Leukemia
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 24, 页码: 22080-22103
作者:
Jiang, Hong
;
Li, Cong
;
Li, Na
;
Sheng, Li
;
Wang, Jingkai
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/01/14
Structural Basis of Main Proteases of Coronavirus Bound to Bofutrelvir
期刊论文
OAI收割
JOURNAL OF MOLECULAR BIOLOGY, 2024, 卷号: 436, 期号: 22, 页码: 16
作者:
Wang, Wei-wei
;
Zeng, Pei
;
Liu, Tongchao
;
Zhou, Xue-lan
;
Lin, Cheng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/10/21
SARS-CoV-2
Coronavirus
Main protease
Mutants
Inhibitor
Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:
Li, Hongrui
;
Liu, Ben-Jin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/08/22
USP1 inhibitor
Structure -activity relationships
Olaparib-resistant cell
Design and synthesis of 1H-pyrazolo[3,4-
d
]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18
作者:
Zhang, Junjie
;
Li, Yan
;
Tang, Haotian
;
Zhou, Qianqian
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/12/08
Cancer immunotherapy
HPK1
Structure -based design
HPK1 inhibitor
Structure-based discovery of potent USP28 inhibitors derived from Vismodegib
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Zhou, Di
;
Xu, Zhuo
;
Huang, Yaodong
;
Wang, Hui
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
USP28
Structure-based
Vismodegib derivatives
Structure-activity relationships
c-Myc
Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20
作者:
Shi, Huanyu
;
Tang, Haotian
;
Li, Yan
;
Chen, Danqi
;
Liu, Tongchao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
Cancer immunotherapy
SAR study
HPK1 inhibitors
Quinazoline-2
5-diamine
IL-2 production
Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20
作者:
Chen, Yuting
;
Shi, Qiongyu
;
Yang, Hong
;
Li, Jiayi
;
Zhou, Kaixin
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/04/10
Epigenetic
PRMT5 inhibitor
Nucleoside derivatives
Structure-activity Relationship Prodrug
Discovery of Novel N-(5-(Pyridin-3-yl)-1H-indazol-3-yl)benzamide Derivatives as Potent Cyclin-Dependent Kinase 7 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 19
作者:
Yang, Bowen
;
Zhang, Haoran
;
Li, Na
;
Gao, Lixin
;
Jiang, Hong
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/04/10
Structure-Based of a Series of NSD2-PWWP1 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9459-9477
作者:
Li, Na
;
Yang, Hong
;
Liu, Ke
;
Zhou, Liwei
;
Huang, Yuting
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/21
In Situ Formation of Polycyclic Aromatic Hydrocarbons as an Artificial Hybrid Layer for Lithium Metal Anodes
期刊论文
OAI收割
NANO LETTERS, 2021, 页码: 8
作者:
Chang, Shaozhong
;
Jin, Xin
;
He, Qiya
;
Liu, Tongchao
;
Fang, Jiabin
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/06/15
polycyclic aromatic hydrocarbons (PAHs)
lithium metal anode
pi-pi stacking
artificial SEI
in situ formation