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浏览/检索结果: 共3725条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24 作者:  Li, Na;  Wang, Linlin;  Hu, Xinyuan;  Xu, Haiyan;  Yang, Bowen   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Voltage-gated sodium channel 1.8  Conformational restriction  Pharmacokinetic  Structure-activity relationship  Analgesic   EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow 期刊论文  OAI收割 ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1 作者:  Jiang, Shuai-Qing;  Xu, Dong;  Hoof, Agnes P. C. van;  Lei, Wei-Hua;  Liu, Yuan   |  收藏  |  浏览/下载：23/0  |  提交时间：2025/07/28 Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20 作者:  Zheng, Fuqiang;  Hu, Zhengtao;  Chen, Hai;  Cheng, Jiaxin;  Hou, Qiongqiong   |  收藏  |  浏览/下载：24/0  |  提交时间：2025/06/23 Heterocycle-fused phenylcyclohexylamines  Multi-target antagonists  NMDAR  Monoamine transporter  Antidepressants   Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins 期刊论文  OAI收割 SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7 作者:  Cao, Zhen;  Aharonian, F.;  Axikegu;  Bai, Y. X.;  Bao, Y. W.   |  收藏  |  浏览/下载：33/0  |  提交时间：2025/06/10 gamma rays  cosmic rays  supernova remnant  young massive cluster  pulsar   The possible "double-bang firecracker" during a solar prominence eruption 期刊论文  OAI收割 Science China: Physics, Mechanics and Astronomy, 2025, 卷号: 68, 期号: 7 作者:  Zheng, Ruisheng;  Liu, Yihan;  Zhong, Ze;  Zhang, Liang;  Wang, Xiaoqian   |  收藏  |  浏览/下载：18/0  |  提交时间：2025/06/10 solar prominence eruptions  coronal mass ejections  coronal pseudostreamers  magnetic reconnecti   The Magnified Waltz: Simulating Light Curves of Binary Stars Passing Through Microcaustics in Strong Lensing Galaxy Clusters 期刊论文  OAI收割 ASTROPHYSICAL JOURNAL, 2025, 卷号: 987, 期号: 1 作者:  Zheng, Wenwen;  Fu, Xiaoting;  Chen, Yang;  Chen XF(陈雪飞);  Guo YJ(郭彦君)   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/07/14 Advancing active compound discovery for novel drug targets: insights from AI-driven approaches 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12 作者:  Wang, Xing-you;  Chen, Yang;  Li, Yu-fan;  Wei, Chao-yang;  Liu, Meng-ya   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/08/20 AI-driven drug discovery  novel drug targets  molecular design  ligand exploration  phenotypic drug discovery  undruggable targets   Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2025, 卷号: 17, 期号: 801, 页码: 18 作者:  Yang, Ruirui;  Wang, Bei;  Su, Zhaoming;  Song, Ying;  Zhang, Yingying   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/08/20 A born ultramassive white dwarf-hot subdwarf super-Chandrasekhar candidate 期刊论文  OAI收割 SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 6 作者:  Luo, Changqing;  Li J(李蛟);  Zheng, Chuanjie;  Liu DD(刘栋栋);  Li ZW(李振威)   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/05/05 stars:horizontal branch  subdwarfs  binaries:close  white dwarfs  stars:neutron  supernovae:general   A post-common-envelope binary with double-peaked Balmer emission lines from TMTS 期刊论文  OAI收割 Astronomy and Astrophysics, 2025, 卷号: 698 作者:  Liu, Qichun;  Wang, Xiaofeng;  Lin, Jie;  Wu CY(吴程远);  Li, Chunqian   |  收藏  |  浏览/下载：16/0  |  提交时间：2025/06/10 techniques: radial velocities  binaries: spectroscopic  stars: evolution  white dwarfs  stars: winds  outflows