中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [34]
化学研究所 [15]
地质与地球物理研究所 [9]
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期刊论文 [105]
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Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:
Chang, Qi
;
Li, Jiayi
;
Deng, Yue
;
Zhou, Ruilin
;
Wang, Bingwei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/25
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity
in
vitro
and
in
vivo
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:
Dong, Sanfeng
;
Hu, Ke
;
Shi, Yulong
;
Wang, Guanli
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/02/19
Multiple myeloma
TRIP13 inhibitor
Cantharidin
DCZ5418
DCZ0415
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants
Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5
作者:
Wang, Yujie
;
Xu, Keshi
;
Liu, Hongchun
;
Zhang, Wei
;
Hu, Chun
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/19
Auristatin E
beta-Glucuronidase
Antiproliferation
Tumor microenvironment
The first record of Lower Cretaceous theropod tracks in Turpan-Hami Basin, Xinjiang, northwestern China
期刊论文
OAI收割
HISTORICAL BIOLOGY, 2023, 页码: 6
作者:
Li, Yang
;
Jiang, Shunxing
;
Yan, Feng
;
Ma, Yingxia
;
Wang, Xiaolin
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/11/02
Theropod tracks
Lower Cretaceous
Hami pterosaur fauna
Turpan-Hami Basin
Xinjiang
Geology, geochronology, and geochemistry of the Gaojiabang tungsten-molybdenum deposit, Anhui Province, Southeast China
期刊论文
OAI收割
ORE GEOLOGY REVIEWS, 2023, 卷号: 157, 页码: 28
作者:
Zheng, Fangshun
;
Qin, Kezhang
;
Cook, Nigel J.
;
Li, Guangming
;
Ciobanu, Cristiana L.
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/29
Gaojiabang
Alteration stages
Porphyry-skarn type deposit
W-Mo mineralization
Ductile deformations
Qingyang-Jiuhua Complex
Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16
作者:
He, Yulong
;
Li, Shunyi
;
Zhu, Yueyue
;
Wang, Yujie
;
Chen, Yuqi
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2023/10/17
Structure-activity relationship
FABP4 inhibitor
Biphenyl scaffold
Selectivity
Oral bioavailability
Anti-inflammation
Nitrogen loss from the coastal shelf of the East China Sea: Implications of the organic matter br
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 854, 页码: 10
作者:
Lai, Xiaoshuang
;
Li, Xuegang
;
Song, Jinming
;
Yuan, Huamao
;
Duan, Liqin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2023/01/04
Nitrogen loss
Organic matter
Denitrification
Anammox
Ladderanes
Functional genes
Application of Pt loaded graphite felt in SO2-depolarized electrolyzer
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 2022, 卷号: 47, 期号: 74, 页码: 31575-31586
作者:
Ma, Xiaoshan
;
Ding, Xifeng
;
Sun, Xinliang
;
Zhang, Ping
;
Wang, Laijun
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/02/24
Hydrogen production
Hybrid sulfur (HyS) process
SO2-depolarized electrolysis (SDE)
Pt-loaded graphite felt
Three-dimensional anode
Influence of bottom seawater oxygen on archaeal tetraether lipids in sediments: Implications for archaeal lipid-based proxies
期刊论文
OAI收割
MARINE CHEMISTRY, 2022, 卷号: 244, 页码: 11
作者:
Guo, Jinqiang
;
Yuan, Huamao
;
Song, Jinming
;
Li, Xuegang
;
Duan, Liqin
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/08/17
Isoprenoid GDGTs
Oxygen
TEX86
Redox proxy