中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
广州地球化学研究所 [45]
上海药物研究所 [37]
自动化研究所 [36]
西北高原生物研究所 [28]
近代物理研究所 [26]
武汉岩土力学研究所 [22]
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iSwitch采集 [17]
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期刊论文 [384]
会议论文 [17]
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2025 [4]
2024 [10]
2023 [19]
2022 [21]
2021 [50]
2020 [41]
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Physics [8]
天文学 [8]
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天文学::天体物理学 [5]
天文学::天体物理学... [4]
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An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Wang, Ze-chen
;
Zeng, Yue
;
Sun, Jin-yuan
;
Chen, Xue-qin
;
Wu, Hao-chen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery
Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 653, 页码: 13
作者:
Sun, Ming-Dao
;
Lin, Qin
;
Ramezani, Jahandar
;
Liu, Jiang-Si
;
Lu, Zheng-An
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/04/03
Early Cretaceous
Aptian
CA-ID-TIMS geochronology
Astrochronology
Carbon isotope stratigraphy
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
Discovery of Novel RNA Demethylase FTO Inhibitors Featuring an Acylhydrazone Scaffold with Potent Antileukemia Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 22
作者:
Liang, Xuewu
;
Huang, Yue
;
Ren, Hairu
;
Liu, Qi
;
Chen, Liang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
Integrative study of lung cancer adeno-to-squamous transition in EGFR TKI resistance identifies RAPGEF3 as a therapeutic target
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 12, 页码: 20
作者:
Wang, Hua
;
Tang, Shijie
;
Wu, Qibiao
;
He, Yayi
;
Zhu, Weikang
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/02/28
EGFR-mutant lung cancer
adeno-to-squamous transition
tyrosine kinase inhibitor resistance
transcription factor network
RAPGEF3
Discovery of a potent PROTAC degrader for RNA demethylase FTO as antileukemic therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5382-5392
作者:
Liu, Lu
;
Qiu, Yuanlai
;
Suo, Yuying
;
Tong, Siyao
;
Wang, Yiqing
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
N 6-Methyladenosine
FTO
PROTAC
RNA epigenetics
Antileukemia
The influence of steep faults at various avoidance distances on the stability of hard rock caverns: Physical model experiments and DEM simulations
期刊论文
OAI收割
TUNNELLING AND UNDERGROUND SPACE TECHNOLOGY, 2024, 卷号: 154, 页码: 16
作者:
Xu, Huai-sheng
;
Li, Shao-jun
;
Xu, Ding-ping
;
Chen, Shi-jie
;
Feng, Guang-liang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/27
Hard rock cavern
Steep fault-cavern distance
Failure mechanism
Physical model experiment
Discrete element method
Observations of cosmic-ray Sun’s shadow with LHAASO-WCDA
会议论文
OAI收割
Nagoya, Japan, 2023-07-26
作者:
Cui, Ming-Yang
;
Xia, Jie
;
He, Jia-Yin
;
Shi, Guang-Lu
;
Feng, Li
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/12/30
Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in
Staphylococcus aureus
期刊论文
OAI收割
PLOS PATHOGENS, 2024, 卷号: 20, 期号: 7, 页码: 32
作者:
Chen, Feifei
;
Zhao, Qingmin
;
Yang, Ziqiong
;
Chen, Rongrong
;
Pan, Huiwen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/11/26
Damage assessment of High-Stress brittle surrounding rock masses in a deep Large-Span High-Sidewall underground Cavern: In situ measurement and numerical simulation
期刊论文
OAI收割
ENGINEERING FAILURE ANALYSIS, 2024, 卷号: 161, 页码: 21
作者:
Huang, Xiang
;
Xu, Ding-Ping
;
Chen, Dong-Fang
;
Li, Chao-Xiang
;
Feng, Guang-Liang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/27
Deep underground cavern
Brittle rock mass
Damage assessment
In situ measurement
Numerical analysis