中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [7]
力学研究所 [1]
上海生物化学与细胞生... [1]
西安光学精密机械研究... [1]
采集方式
OAI收割 [10]
内容类型
期刊论文 [9]
会议论文 [1]
发表日期
2025 [1]
2024 [1]
2023 [1]
2022 [4]
2021 [1]
2020 [1]
更多
学科主题
筛选
浏览/检索结果:
共10条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 25
作者:
Lu, Yuhang
;
Yan, Ziqin
;
Sun, Jiaqi
;
Wang, Chenxu
;
Xu, Lan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 36
作者:
Lou, Jianfeng
;
Zhou, Qianqian
;
Lyu, Xilin
;
Cen, Xinyi
;
Liu, Chen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/22
Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 17
作者:
Yan, Ziqin
;
Lyu, Xilin
;
Lin, Dongze
;
Wu, Gaoxing
;
Gong, Yang
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2023/10/17
A chemical perspective on the modulation of TEAD transcriptional activities: Recent progress, challenges, and opportunities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243, 页码: 31
作者:
Lou, Jianfeng
;
Lu, Yuhang
;
Cheng, Jing
;
Zhou, Feilong
;
Yan, Ziqin
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/12/13
TEAD
YAP
Palmitoylation
Protein-protein interaction
Covalent inhibitor
Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 114327
作者:
Feng, Xuexin
;
Yan, Ziqin
;
Zhou, Feilong
;
Lou, Jianfeng
;
Lyu, Xilin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/03/21
BFL-1
Apoptosis
Covalent inhibitor
Cytochrome c
BCL-2
Protein-Protein interaction
Structure-Based Discovery of MDM2/4 Dual Inhibitors that Exert Antitumor Activities against MDM4-Overexpressing Cancer Cells
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 8, 页码: 6207-6230
作者:
Zhang, Shiyan
;
Yan, Ziqin
;
Li, Yafang
;
Gong, Yang
;
Lyu, Xilin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/08/16
Material properties of phase-separated TFEB condensates regulate the autophagy-lysosome pathway
期刊论文
OAI收割
JOURNAL OF CELL BIOLOGY, 2022, 卷号: 221, 期号: 5, 页码: 27
作者:
Wang, Zheng
;
Chen, Di
;
Guan, Dongshi
;
Liang, Xiaobo
;
Xue, Jianfeng
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/11/14
Recent Progress and Clinical Development of Inhibitors that Block MDM4/p53 Protein-Protein Interactions
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 10621-10640
作者:
Zhang, Shiyan
;
Lou, Jianfeng
;
Li, Yafang
;
Zhou, Feilong
;
Yan, Ziqin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
Mapping diffuse emission in lyman UV band
会议论文
OAI收割
Virtual, Online, CA, United states, 2020-12-14
作者:
Ji, Li
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/02/05
Small Explorer
ultraviolet
line emission
Heterogeneous mutation pattern in tumor tissue and circulating tumor DNA warrants parallel NGS panel testing
期刊论文
OAI收割
MOLECULAR CANCER, 2018, 卷号: 17, 期号: 1, 页码: 131
作者:
Guo, Qiaomei
;
Wang, Lin
;
Hu, Xiaomeng
;
Yu, Wenjun
;
Lou, Jiatao
  |  
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2019/04/28
Lung-cancer
Evolution