中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [40]
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期刊论文 [75]
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Chemical Space Profiling of SARS-CoV-2 PL
pro
Using DNA-Encoded Focused Libraries
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 10
作者:
Wang, Xudong
;
Zhu, Ying
;
Zhao, Qingyi
;
Lu, Weiwei
;
Xu, Yechun
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
DNA-Encoded Focused Libraries (DEFLs)
SARS-CoV-2
Papain-like Protease
Library Design
ProteinInhibitors
A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3778-3794
作者:
Guan, Dongliang
;
Liu, Jiaxiang
;
Chen, Feifei
;
Li, Jian
;
Wang, Xiaowen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/05/07
Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1079-1092
作者:
Qin, Shaozhao
;
Feng, Lijian
;
Zhao, Qingyi
;
Yan, Ziqin
;
Lyu, Xilin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 46, 页码: 25283-25292
作者:
Jiang, Lulu
;
Liu, Sixiu
;
Jia, Xinglong
;
Gong, Qinting
;
Wen, Xin
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/01/16
Increased Grain Crop Production Intensifies the Water Crisis in Northern China
期刊论文
OAI收割
EARTHS FUTURE, 2023, 卷号: 11, 期号: 9, 页码: 31
作者:
Li, Xiaojie
;
Zhang, Yongqiang
;
Ma, Ning
;
Zhang, Xuanze
;
Tian, Jing
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/10/23
agricultural water consumption
crop production
coupled carbon-water model
irrigation demand
terrestrial water storage
Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Wen, Xin
;
Zhang, Minmin
;
Duan, Zhiqiang
;
Suo, Yanrui
;
Lu, Weiwei
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/10/17
Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 14, 期号: 8, 页码: 1073-1078
作者:
Seydimemet, Mengnisa
;
Yang, Yixuan
;
Lv, Yuhan
;
Liu, Jiaxiang
;
Yan, Ziqin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
DNA-encoded library technology
Pyrimidine-focusedDNA-encodedlibrary
BRD4
Affinity screening
Inhibitor
Sequence-based drug design as a concept in computational drug design
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21
作者:
Chen, Lifan
;
Fan, Zisheng
;
Chang, Jie
;
Yang, Ruirui
;
Hou, Hui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Biological Function of Pin1 in Vivo and Its Inhibitors for Preclinical Study: Early Development, Current Strategies, and Future Directions
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 14, 页码: 9251-9277
作者:
He, Siyu
;
Li, Linjie
;
Jin, Rui
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Structure-Activity Relationship Study of 1H-Pyrrole-3-carbonitrile Derivatives as STING Receptor Agonists
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 9
作者:
Shen, Chang
;
Xu, Peijia
;
Zhang, Changfa
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
cGAS-STING signaling pathway
STING agonists
antitumor immunity
anti-infection immunity