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A strategy to boost xanthine oxidase and angiotensin converting enzyme inhibitory activities of peptides via molecular docking and module substitution
期刊论文
OAI收割
FOOD CHEMISTRY, 2024, 卷号: 442, 页码: 9
作者:
Meng, Pengfei
;
Wang, Yanxin
;
Huang, Yumeng
;
Liu, Tong
;
Ma, Mingxia
  |  
收藏
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浏览/下载:0/0
  |  
提交时间:2024/05/07
Peptide
Activity boosting strategy
Molecular docking
Module substitution
Xanthine oxidase inhibitory
Angiotensin-converting enzyme inhibitory
Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
期刊论文
OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:
Bian, Yi-cong
;
Meng, Jian
;
Hu, Tao
;
Ma, Sheng
;
Huang, Chen-rong
  |  
收藏
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浏览/下载:0/0
  |  
提交时间:2024/05/22
HSK7653
long-acting dipeptidyl peptidase-4 inhibitor
mass balance
metabolism
pharmacokinetics
radiolabelled
Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 20
作者:
Niu, Pengpeng
;
Tao, Yanxin
;
Lin, Guohao
;
Xu, Huiqi
;
Meng, Qingyuan
  |  
收藏
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浏览/下载:0/0
  |  
提交时间:2024/05/22
The development of logic gate-based fluorescent probes that respond to intracellular hydrogen peroxide and pH in tandem
期刊论文
OAI收割
TALANTA, 2024, 卷号: 270, 页码: 8
作者:
Han, Hai-Hao
;
Liu, Meng-Jiao
;
Zhang, Weijian
;
Sun, Lu-Lu
;
Ma, Xiuhua
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/19
Reactive oxygen species (ROS)
pH
Logic gate
Fluorescent probe
Cell imaging
Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner
期刊论文
OAI收割
METABOLISM-CLINICAL AND EXPERIMENTAL, 2024, 卷号: 152, 页码: 12
作者:
Meng, Meiyao
;
Cao, Yuxiang
;
Qiu, Jin
;
Shan, Guangyu
;
Wang, Yingwen
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/25
Triglyceride metabolism
ZNF638
Adipose tissue
Angptl8
Lipoprotein lipase
Quantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting the PDGFRβ/PI3K/AKT pathway
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Meng, Qian
;
Zhu, Hongwen
;
Li, Yuanyuan
;
Peng, Xiaotian
;
Wang, Tianming
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Yinchenzhufu decoction
proteomics
cholestasis
liver fibrosis
PDGFR beta/PI3K/AKT
Discovery of Pyrido[2,3-
d
]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3986-4006
作者:
Sun, Yaoliang
;
Chen, Manman
;
Han, Yuyan
;
Li, Weiqiang
;
Ma, Xiaoyu
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收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Spatial patterns of light response parameters and their regulation on gross primary productivity in China
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2024, 卷号: 345, 页码: 11
作者:
Lin, Yong
;
Chen, Zhi
;
Yu, Guirui
;
Yang, Meng
;
Hao, Tianxiang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/01/22
Light response parameter
Apparent quantum yield (alpha)
Maximum gross photosynthetic rate ( A max )
Spatial heterogeneity
Eddy covariance
High spatial variability in water use efficiency of terrestrial ecosystems throughout China is predominated by biological factors
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2024, 卷号: 345, 页码: 109834
作者:
Dou, Xiaojun
;
Yu, Guirui
;
Chen, Zhi
;
Yang, Meng
;
Hao, Tianxiang
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/02/05
Water use efficiency
Spatial variability
Influencing factors
Driving mechanism
Eddy covariance
Terrestrial ecosystems
Influence of loneliness burden on cardio-cerebral vascular disease among the Chinese older adult: a national cohort study
期刊论文
OAI收割
FRONTIERS IN PUBLIC HEALTH, 2024, 卷号: 12, 页码: 9
作者:
Wu, Dishan
;
Hu, Xing
;
Meng, Lingbing
;
Li, Jianyi
;
Xu, Jiapei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/04/01
loneliness
cardio-cerebral vascular diseases
cumulative burden
older adult
longitudinal change