机构

• 广州能源研究所 [22]
• 上海药物研究所 [13]
• 金属研究所 [7]
• 海洋研究所 [2]
• 力学研究所 [1]
• 物理研究所 [1]
• 更多

采集方式

• OAI收割 [55]
• iSwitch采集 [1]

内容类型

• 期刊论文 [55]
• CNKI期刊论文 [1]

发表日期

• 2025 [3]
• 2024 [6]
• 2023 [2]
• 2022 [3]
• 2021 [15]
• 2020 [1]
• 更多

学科主题

• Biochemist... [1]

筛选

浏览/检索结果: 共56条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择作者升序作者降序发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序 Discovery and Identification of a Novel PORCN Inhibitor via Structure-Based Virtual Screening 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2025, 卷号: 20, 期号: 6, 页码: 1319-1332 作者:  Yang, Xinyu;  Li, Yanbei;  Zhou, Jingyi;  Zhou, Yuanyang;  Lin, Kexin   |  收藏  |  浏览/下载：30/0  |  提交时间：2025/07/25 Discovery of 3-(Fluoro-imidazolyl)pyridazine Derivatives as Potent STING Agonists with Antitumor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 9864-9885 作者:  Hou, Hui;  Zhou, Jingyi;  Sui, Qibang;  Zhang, Changfa;  Su, Zhaoming   |  收藏  |  浏览/下载：33/0  |  提交时间：2025/07/25 Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel HsClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307 作者:  Sun, Mingyang;  Chen, Beijing;  Teng, Dan;  Zhao, Hongshen;  Liao, Yilie   |  收藏  |  浏览/下载：97/0  |  提交时间：2025/04/01 Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21 作者:  Chen, Beijing;  Sun, Mingyang;  Zhang, Chun;  Huang, Qi;  Teng, Dan   |  收藏  |  浏览/下载：82/0  |  提交时间：2024/12/25 An updated patent review of SOS1 inhibitors (2022-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2024, 页码: 15 作者:  Zhou, Guizhen;  Zhou, Chuan;  Ma, Xinyi;  Xu, Jiahang;  Zhou, Zehui   |  收藏  |  浏览/下载：49/0  |  提交时间：2024/12/11 SOS1  KRAS  cancer  inhibitor  drug discovery   Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11 期刊论文  OAI收割 CELL METABOLISM, 2024, 卷号: 36, 期号: 10, 页码: 25 作者:  Zhou, Bing;  Luo, Yunchen;  Bi, Hanqi;  Zhang, Ni;  Ma, Mingyue   |  收藏  |  浏览/下载：67/0  |  提交时间：2024/11/26 Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseases 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2024, 页码: 14 作者:  Zhang, Yinghui;  Liu, Yadan;  Jiang, Bing;  Chen, Lifan;  Hu, Jie   |  收藏  |  浏览/下载：54/0  |  提交时间：2024/10/21 cGAS-STING signaling  STING inhibitor  TransformerCPI model  Licochalcone D  inflammatory diseases   Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido [2,3- d ]pyrimidin-7-one-based SOS1 inhibitor 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 9 作者:  Wang, Kun;  Zhou, Zehui;  Ma, Xinyi;  Xu, Jiahang;  Xu, Wangyang   |  收藏  |  浏览/下载：59/0  |  提交时间：2024/07/12 SOS1  KRAS mutation  PROTAC  Anti-cancer activity   Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14 作者:  Xie, Xiong;  Lan, Qiaoshuai;  Zhao, Jinyi;  Zhang, Sulin;  Liu, Lu   |  收藏  |  浏览/下载：79/0  |  提交时间：2024/05/07 Precise measurement method of carrier motion state in microgravity environment 期刊论文  OAI收割 MEASUREMENT, 2023, 卷号: 222, 页码: 17 作者:  Liu, Mingyue;  Zhu, Huizhong;  Xu, Xinchao;  Ma, Youqing;  Zhang, Shuo   |  收藏  |  浏览/下载：50/0  |  提交时间：2023/11/28 Multi-camera calibration  Stereo vision  Extraction of homonymous points  Random Sample Consensus (RANSAC)  Carrier motion state