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Chinese Academy of Sciences Institutional Repositories Grid
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Design, synthesis, and activity evaluation of indole derivatives as potential stabilizers for p53 Y220C
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 121, 页码: 9
作者:
Li, Linquan
;
Gu, Xi
;
Meng, Jingyi
;
Wen, Yiming
;
Yi, Jing
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/05/27
p53 Y220C
Synthesis
Structural modification
Drug design
Deformation Rate Effects in the Circumferential Strain-Controlled Post-Peak Loading Tests
期刊论文
OAI收割
ROCK MECHANICS AND ROCK ENGINEERING, 2025, 页码: 22
作者:
Cui, Guanghao
;
Meng, Fanzhen
;
Wang, Wei
;
Liu, Pengyuan
;
Wen, Yuantao
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/27
Circumferential deforming rate
Brittle rock
Post-peak curve
Failure mode
Acoustic emission (AE) characteristics
Discovery and Extensive Follow-up of SN 2024ggi, a Nearby Type IIP Supernova in NGC 3621
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 983, 期号: 1
作者:
Chen, Ting-Wan
;
Yang, Sheng
;
Srivastav, Shubham
;
Moriya, Takashi J.
;
Smartt, Stephen J.
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2025/04/21
Glabridin as a selective Kv2.1 inhibitor ameliorates DPN pathology by disrupting the Aβ/Kv2.1/JNK/NF-κB/NLRP3/p-Tau pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 17
作者:
Xu, Jia-wen
;
Ma, Lin
;
Xiang, Yu
;
Dai, Meng-qing
;
Li, Qiu-hui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/27
diabetic peripheral neuropathy
glabridin
Kv2.1
dorsal root ganglia
Schwann cells
A beta/Kv2.1/NLRP3/p-Tau axis
Enhanced early strength and microstructural stability of dredged sludge using CPCS curing agent
期刊论文
OAI收割
CONSTRUCTION AND BUILDING MATERIALS, 2025, 卷号: 466, 页码: 16
作者:
Dong, Meng
;
Wen, Xiaodong
;
Lang, Lei
;
Jin, Jiaxu
;
Li, Jiang-Shan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/27
Dredged sludge
Curing agent
Mechanical properties
Microscopic properties
Solidification mechanism
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Role of Unloading Rate and Minimum Principal Stress on Fault Activation with Implication in Fault-Slip Rockburst
期刊论文
OAI收割
ROCK MECHANICS AND ROCK ENGINEERING, 2025, 页码: 24
作者:
Wang, Wei
;
Meng, Fanzhen
;
Tian, Dongliang
;
Wen, Yuantao
;
Yue, Zhufeng
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/27
Fault-slip rockburst
Unloading rate
Fault activation
Initial minimum principal stress
Time-delayed failure
Molecular basis of lipid and ligand regulation of prostaglandin receptor DP2
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 51, 页码: 12
作者:
Xu, Jiuyin
;
Xu, Youwei
;
Hou, Li
;
He, Xinheng
;
Li, Yang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/02/28
prostaglandin receptor
DP2
lipid regulation
receptor activation
signal bias
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/04/01
Integration of ion mobility-quadrupole time-of-flight mass spectrometry and triple quadrupole-ion trap mass spectrometry coupled with ultra-high performance liquid chromatography for characterizing and quantitatively assay the saponins of
Panax
quinquefolius
flower
期刊论文
OAI收割
MICROCHEMICAL JOURNAL, 2024, 卷号: 207, 页码: 14
作者:
Wang, Yu
;
Hong, Li-li
;
Sun, Meng-xiao
;
Li, Xue
;
Zou, Ya-dan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/16
Panax quinquefolius flower
UHPLC/IM-QTOF-MS
UHPLC/QTrap-MS
Multi-component characterization
Quantitative assay