中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
国家天文台 [3]
力学研究所 [1]
理论物理研究所 [1]
中国科学院大学 [1]
云南天文台 [1]
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OAI收割 [13]
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期刊论文 [14]
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2021 [5]
2020 [1]
2019 [1]
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Multidisci... [1]
Physics [1]
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Taiji program in space for gravitational universe with the first run key technologies test in Taiji-1
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MODERN PHYSICS A, 2021, 卷号: 36, 期号: 11N12, 页码: 2
作者:
Wu YL(吴岳良)
;
Luo ZR(罗子人)
;
Wang, Jian-Yu
;
Bai, Meng
;
Bian, Wei
  |  
收藏
  |  
浏览/下载:161/0
  |  
提交时间:2021/06/21
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells
期刊论文
OAI收割
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:
Wang, Yu-xiang
;
Zhang, Xu
;
Ma, Qing-yang
;
Hu, Lan-dian
;
Zhang, Xi
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/05/24
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:
Xiang, Hao-Yue
;
Wang, Xiang
;
Chen, Yan-Hong
;
Zhang, Xi
;
Tan, Cun
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
PI3K
Pyrrolo[2,1-f][1,2,4]triazine
Anti-cancer
Target therapy
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
期刊论文
OAI收割
AUTOPHAGY, 2021, 卷号: 17
作者:
Klionsky, Daniel J.
;
Abdel-Aziz, Amal Kamal
;
Abdelfatah, Sara
;
Abdellatif, Mahmoud
;
Abdoli, Asghar
  |  
收藏
  |  
浏览/下载:318/0
  |  
提交时间:2021/05/31
Autophagosome
cancer
flux
LC3
lysosome
macroautophagy
neurodegeneration
phagophore
stress
vacuole
Taiji program in space for gravitational universe with the first run key technologies test in Taiji-1
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MODERN PHYSICS A, 2021, 卷号: 36, 期号: 11N12, 页码: 2102002
作者:
Wu, Yue-Liang
;
Luo, Zi-Ren
;
Wang, Jian-Yu
;
Bai, Meng
;
Bian, Wei
  |  
收藏
  |  
浏览/下载:106/0
  |  
提交时间:2021/09/27
Blue Large-amplitude Pulsators: The Possible Surviving Companions of Type Ia Supernovae
期刊论文
OAI收割
The Astrophysical Journal, 2020, 卷号: 903, 期号: 2
作者:
Meng,Xiang-Cun
;
Han,Zhan-Wen
;
Podsiadlowski,Philipp
;
Li,Jiao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/12/06
Type Ia supernovae
White dwarf stars
Variable stars
Supernova remnants
Unbiased screening reveals that blocking exportin 1 overcomes resistance to PI3K alpha inhibition in breast cancer
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2019, 卷号: 4, 页码: 3
作者:
Liu, Xue-Ling
;
Wang, Bo-Bo
;
Wang, Yi
;
Wang, Yu-Xiang
;
Yang, Chun-hao
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Discovery of clinical candidate methyl (5-(6-((4(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) : A highly potent and selective PI3K alpha inhibitor for the treatment of advanced solid tumors
期刊论文
OAI收割
CANCER RESEARCH, 2018, 卷号: 78, 期号: 13, 页码: 2
作者:
Xiang, Haoyue
;
Wang, Xiang
;
Chen, Yanhong
;
Zhang, Xi
;
Chen, Yi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Why Are Peculiar Type Ia Supernovae More Likely to Show the Signature of a Single-degenerate Model?
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2018, 卷号: 855, 期号: 2
作者:
Meng XC(孟祥存)
;
Han ZW(韩占文)
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2018/04/24
Ism: Supernova Remnants
Supernovae: General
White Dwarfs
Decrease in phosphorylated ERK indicates the therapeutic efficacy of a clinical PI3K alpha-selective inhibitor CYH33 in breast cancer
期刊论文
OAI收割
CANCER LETTERS, 2018, 卷号: 433, 页码: 273-282
作者:
Liu, Xue-ling
;
Xu, Yi-chao
;
Wang, Yu-xiang
;
Chen, Yi
;
Wang, Bo-bo
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
PIK3CA
HER2
Akt
Patient-derived xenograft (PDX)