中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
西北高原生物研究所 [1]
地球化学研究所 [1]
海洋研究所 [1]
自动化研究所 [1]
采集方式
OAI收割 [11]
内容类型
期刊论文 [11]
发表日期
2023 [2]
2022 [4]
2021 [1]
2020 [1]
2019 [2]
2011 [1]
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Isolation and characterization of glutathione S-transferase genes and their transcripts in
Saccharina japonica
(Laminariales, Phaeophyceae) during development and under abiotic stress
期刊论文
OAI收割
BMC PLANT BIOLOGY, 2023, 卷号: 23, 期号: 1, 页码: 19
作者:
Lu, Chang
;
Zhang, Pengyan
;
Li, Shuang
;
Cheng, Mengzhen
;
Duan, Delin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/11/30
Saccharina japonica
Glutathione S-transferase
Transcriptome
Gene expression
Abiotic stresses
Enzyme activity assay
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:130/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-GenerationEpidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 9, 页码: 6840-6858
作者:
Chen, Hao
;
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Yuqing
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/03/21
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-GenerationEpidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations br
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 9, 页码: 6840-6858
作者:
Chen, Hao
;
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Yuqing
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/16
Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR(T790M/C797S) Mutants
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 7
作者:
Li, Shan
;
Zhang, Tao
;
Zhu, Su-Jie
;
Lei, Chong
;
Lai, Mengzhen
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/06/15
Epidermal Growth Factor Receptor (EGFR)
Resistant Mutation
C797S
Antitumor
Carbon, Nitrogen and Phosphorus Stoichiometry and Its Influencing Factors in Karst Primary Forest
期刊论文
OAI收割
Forests, 2022, 卷号: 13, 期号: 12
作者:
Chen Zhang
;
Fuping Zeng
;
Zhaoxia Zeng
;
Hu Du
;
Lijin Zhang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/06/29
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:113/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:
Hu, Xianglong
;
Xun, Qiuju
;
Zhang, Tao
;
Zhu, Su-Jie
;
Li, Qian
  |  
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2020/07/01
EGFR(C797S) mutant
SARs
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidine
Clinical resistance
Fourth-generation inhibitors
Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFR(L858R/T790M/C797S))
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7302-7308
作者:
Shen, Jiayi
;
Zhang, Tao
;
Zhu, Su-Jie
;
Sun, Min
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
Highly fluorescent N-doped carbon dots with two-photon emission for ultrasensitive detection of tumor marker and visual monitor anticancer drug loading and delivery
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2019, 卷号: 356
作者:
Gong, Peiwei
;
Sun, Lu
;
Wang, Fei
;
Liu, Xicheng
;
Yan, Zhengquan
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2019/11/26
Carbon dots
Inner filter effect
beta-Glucuronidase
Nanocarrier
Chemotherapy